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ClinicalTrials.gov 12 recruiting now official registry

Inflammatory Bowel Disease clinical trials

Every US clinical trial registered for Inflammatory Bowel Disease — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

29 US clinical trials · 12 currently recruiting

The research picture

Inflammatory Bowel Disease has 29 registered US clinical trials, 12 of them open to new participants right now — about 41% of the total.

12
recruiting participants now
41%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
3
top sponsor: Icahn School of Medicine at Mount Sinai

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,500 participants

A Multicenter National Prospective Study of Pregnancy and Neonatal Outcomes in Women With Inflammatory Bowel Disease

University of California, San Francis

NCT00904878

RECRUITING 1,000 participants

Immune Regulation in Ulcerative Colitis or Crohn s Disease

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001184

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING NA 250 participants

Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease

VA Office of Research and Development

NCT07210580

RECRUITING 125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

M.D. Anderson Cancer Center

NCT04751396

RECRUITING 92 participants

Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

Massachusetts General Hospital

NCT04508088

RECRUITING NA 90 participants

Effect of Mediterranean Diet in Inflammatory Bowel Disease

University of California, San Diego

NCT05973500

RECRUITING NA 75 participants

The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

Stanford University

NCT03615690

RECRUITING 50 participants

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

Boston Children's Hospital

NCT04331639

RECRUITING 46 participants

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

Icahn School of Medicine at Mount Sinai

NCT06001450

RECRUITING NA 30 participants

Impact of Morning Light Therapy in IBD

Icahn School of Medicine at Mount Sinai

NCT07207200

RECRUITING NA 30 participants

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

Rush University Medical Center

NCT05579392

ACTIVE NOT RECRUITING 2,500 participants

Johns Hopkins Crohn's Disease and Ulcerative Colitis Study

Johns Hopkins University

NCT01169207

ACTIVE NOT RECRUITING 2,400 participants

Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS)

Johns Hopkins University

NCT01169194

COMPLETED Phase 3 769 participants

A Study to Evaluate the Safety and Efficacy of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease Who Have Failed or Are Intolerant to Tumor Necrosis Factor (TNF) Antagonist Therapy (UNITI-1)

Janssen Research & Development

NCT01369329

COMPLETED Phase 3 443 participants

Open-Label, Long-term Balsalziade Disodium Tablet Ulcerative Colitis Study

Bausch Health Americas

NCT00486031

COMPLETED Phase 3 348 participants

Telemedicine in Patients With Inflammatory Bowel Disease (TELE-IBD)

University of Maryland, Baltimore

NCT01692743

COMPLETED NA 320 participants

Trial on Impact of HealthPROMISE Mobile App on Inflammatory Bowel Disease Care and Quality of Life

Icahn School of Medicine at Mount Sinai

NCT02322307

COMPLETED Phase 3 250 participants

Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous Iron To Treat Iron Deficiency Anaemia in IBD

Shield Therapeutics

NCT02680756

COMPLETED 171 participants

Value of Fecal Calprotectin

Indiana University

NCT00577928

COMPLETED NA 140 participants

Improving Medication Adherence in Pediatric Inflammatory Bowel Disease

Children's Hospital Medical Center, Cincinnati

NCT01536509

COMPLETED Phase 2 105 participants

A Trial of Rosiglitazone for Ulcerative Colitis

James Lewis

NCT00065065

COMPLETED Phase 1 73 participants

Dietary Treatment of Crohn's Disease

Rush University Medical Center

NCT00343642

COMPLETED NA 69 participants

Pneumococcal Vaccination in Patients With Inflammatory Bowel Disease

Cedars-Sinai Medical Center

NCT00829595

COMPLETED NA 55 participants

Ulcerative Colitis Relapse Prevention Trial, Hypnosis

Northwestern University

NCT00798642

COMPLETED NA 41 participants

Treatment of Depressed Adolescents With Physical Illness

University of Pittsburgh

NCT00446238

COMPLETED Phase 4 15 participants

Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease

Mayo Clinic

NCT01034358

COMPLETED Phase 1 11 participants

Early Serum Infliximab Levels in Severe Ulcerative Colitis.

University of California, San Francis

NCT01971814

COMPLETED Phase 1 8 participants

A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis

University of Minnesota

NCT02464020

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 1
Phase 3 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Inflammatory Bowel Disease Trial Landscape

ClinicalTrials.gov lists 29 US studies indexed under Inflammatory Bowel Disease, and 12 of those are currently open to recruitment — roughly 41% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Inflammatory Bowel Disease shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Inflammatory Bowel Disease is led by Icahn School of Medicine at Mount Sinai with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 29 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Inflammatory Bowel Disease?

PlainTrial tracks 29 US clinical trials for Inflammatory Bowel Disease, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Inflammatory Bowel Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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