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NCT04508088 · ClinicalTrials.gov registry record
Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease
A clinical trial of Crohn Disease and Inflammatory Bowel Disease, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- 92
- Enrollment target
- 1
- Study location
NCT04508088 is a study of Crohn Disease and Inflammatory Bowel Disease that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 92 participants, below the 204-participant average among 71 other Crohn Disease trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04508088, a study of Crohn Disease and Inflammatory Bowel Disease, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- 92 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-energy X-ray absorptiometry and peripheral quantitative computed tomography. This longitudinal project will focus on abnormalities in bone marrow composition, and specifically whether adolescents with newly diagnosed CD exhibit increased bone marrow fat, its association with bone mineral density (BMD) and the underlying pathophysiology, including bone turnover markers and immune cellular/molecular parameters.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood Draw
- DIAGNOSTIC_TEST Magnetic resonance spectroscopy
- DIAGNOSTIC_TEST Coronal T1 weighted spin echo images
- DIAGNOSTIC_TEST Spin-lattice relaxation (T1)
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2020-09-10 |
| Est. Completion | 2026-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04508088
The ClinicalTrials.gov registry entry for NCT04508088 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 92 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 204-participant average among 71 other Crohn Disease trials with a reported enrollment target (55% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Crohn Disease appearing as the primary indexed condition, and to 4 interventions - of which Blood Draw is the first listed.
NCT04508088 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04508088 about?
NCT04508088 is a clinical study titled "Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease". The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-e...
What is the current status of trial NCT04508088?
This trial is currently recruiting. The enrollment target is 92 participants. The study started on 2020-09-10. Estimated completion is 2026-12.
What conditions does trial NCT04508088 study?
This clinical trial studies the following conditions: Crohn Disease, Inflammatory Bowel Disease.
What interventions are being tested in trial NCT04508088?
The interventions under investigation include: Blood Draw (DIAGNOSTIC_TEST), Magnetic resonance spectroscopy (DIAGNOSTIC_TEST), Coronal T1 weighted spin echo images (DIAGNOSTIC_TEST), Spin-lattice relaxation (T1) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04508088?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04508088 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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