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ClinicalTrials.gov 5 recruiting now full pipeline small index

Immunoglobulin A Nephropathy: full-pipeline trial registry

5 of 14 indexed Immunoglobulin A Nephropathy trials are currently recruiting.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 5 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Immunoglobulin A Nephropathy: 14 US clinical trials tracked, 5 recruiting.

Immunoglobulin A Nephropathy is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Travere Therapeutics, running 4 of these trials.

Enrollment posture brief

Registry condition immunoglobulin-a-nephropathy

OPEN 5 | RECR 36% | LATE 7 | EARLY 5 | RANK #1230 | SPON 4

Nearest open-share peer: Attention (36% recruiting · 14 trials)

Immunoglobulin A Nephrop (th…36%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Immunoglobulin A Nephropathy

Immunoglobulin A Nephropathy lists 5 open slots (36% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Immunoglobulin A Nephropathy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Immunoglobulin A Nephropathy is recruiting below its size-band peers.

    5 of 14 indexed trials (35.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Immunoglobulin A Nephropathy research.

    Travere Therapeutics accounts for 4 of 14 trials (28.6%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Typical Immunoglobulin A Nephropathy enrolment sits around 383 participants.

    Median target enrolment is 383 among the 14 trials that report a genuine target (sentinel values excluded). 5 of those (35.7%) plan for fewer than 100 participants.

  4. Immunoglobulin A Nephropathy research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 24Phase 37

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 3 510 participants

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

Alexion Pharmaceuticals

NCT06291376

RECRUITING 300 participants

A Mobile App-Based Study to Evaluate Disease Burden and Treatment Patterns in Immunoglobulin A Nephropathy (IgAN) in the US

Novartis Pharmaceuticals

NCT06952426

RECRUITING Phase 2 67 participants

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Travere Therapeutics

NCT05003986

RECRUITING Phase 3 24 participants

Study of Ravulizumab in Pediatric Participants With Primary IgAN

Alexion Pharmaceuticals

NCT07024563

RECRUITING Phase 2 20 participants

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

Novartis Pharmaceuticals

NCT06797518

ACTIVE NOT RECRUITING Phase 3 605 participants

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

Alpine Immune Sciences Inc, A Subsidiary of Vertex

NCT06564142

ACTIVE NOT RECRUITING Phase 3 530 participants

Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)

Otsuka Pharmaceutical Development & Commercialization

NCT05248646

ACTIVE NOT RECRUITING Phase 3 406 participants

A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy

Travere Therapeutics

NCT03762850

ACTIVE NOT RECRUITING Phase 3 404 participants

Atrasentan in Patients With IgA Nephropathy

Chinook Therapeutics

NCT04573478

ACTIVE NOT RECRUITING Phase 3 383 participants

A Study of Zigakibart in Adults With IgA Nephropathy

Novartis Pharmaceuticals

NCT05852938

ACTIVE NOT RECRUITING Phase 2 103 participants

Atrasentan in Patients With Proteinuric Glomerular Diseases

Novartis Pharmaceuticals

NCT04573920

ACTIVE NOT RECRUITING Phase 1 72 participants

An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases

Alpine Immune Sciences

NCT05732402

COMPLETED 487 participants

Humanistic Burden of (FSGS) Focal Segmental Glomerulosclerosis and IgAN (Immunoglobulin A Nephropathy)

Travere Therapeutics

NCT05200871

COMPLETED Phase 2 48 participants

A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN

Travere Therapeutics

NCT05856760

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4
Phase 3 7

Named interventions

Most-linked intervention names on Immunoglobulin A Nephropathy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
Atrasentan Drug
2 trials
Povetacicept Drug
2 trials
Sparsentan Drug
2 trials
Ravulizumab Drug
2 trials
irbesartan Drug
1 trials
Placebo (matched to Povetacicept) Drug
1 trials
Sibeprenlimab 400 mg Drug
1 trials

US sites by state

Facility locations filed on Immunoglobulin A Nephropathy trials. A trial with sites in several states counts in each.

California 13 trials
Colorado 9 trials
Florida 8 trials
Alabama 8 trials
Georgia 6 trials
Pennsylvania 5 trials
New York 5 trials
North Carolina 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Immunoglobulin A Nephropathy page

14 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Immunoglobulin A Nephropathy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Travere Therapeutics sponsors the most Immunoglobulin A Nephropathy trials on record, review their full trial history before evaluating a specific study. See Travere Therapeutics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Immunoglobulin A Nephropathy condition card totals 14 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.