Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hypertrophic Scar: early-phase trial registry
2 of 8 indexed Hypertrophic Scar trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 2 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Hypertrophic Scar: 8 US clinical trials tracked, 2 recruiting.
Hypertrophic Scar is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is RXi Pharmaceuticals, running 1 of these trials.
Enrollment posture brief
Registry condition hypertrophic-scar
OPEN 2 | RECR 25% | LATE 0 | EARLY 3 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Pain (25% recruiting · 20 trials)
Hypertrophic Scar lists 2 open slots (25% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertrophic Scar on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Hypertrophic Scar is recruiting below its size-band peers.
2 of 8 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Hypertrophic Scar trials is spread across many organizations.
RXi Pharmaceuticals accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
-
Most Hypertrophic Scar trials plan to enrol fewer than 100 people.
Median target enrolment is 30 among the 8 trials that report a genuine target (sentinel values excluded). 8 of those (100%) plan for fewer than 100 participants.
-
Hypertrophic Scar research is mostly interventional.
7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy
University of California, San Francisco
NCT07147166
Zinc Oxide Versus Petrolatum Following Skin Surgery
Melissa Pugliano-Mauro
NCT03561376
Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization
Henry Ford Health System
NCT05478551
"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"
The Center for Clinical and Cosmetic Research
NCT04169490
Characterization of Dyschromic Hypertrophic Scar
Medstar Health Research Institute
NCT04619589
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery in Healthy Adults
RXi Pharmaceuticals
NCT02030275
Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars.
The Metis Foundation
NCT04769089
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
Massachusetts General Hospital
NCT03692273
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertrophic Scar records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertrophic Scar trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertrophic Scar page
8 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Hypertrophic Scar trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- RXi Pharmaceuticals sponsors the most Hypertrophic Scar trials on record, review their full trial history before evaluating a specific study. See RXi Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertrophic Scar condition card totals 8 registered trials; most-linked intervention Active Comparator Silicone Gel (Kelo-Cote) + FS2 Emulsion Moisturizer; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.