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NCT04769089 · ClinicalTrials.gov registry record · NA

Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars.

A NA study of Hypertrophic Scar, sponsored by The Metis Foundation.

Completed
Registry status
NA
Development phase
25
Enrollment target
1
Study location

NCT04769089 is a NA study of Hypertrophic Scar that has completed, run by The Metis Foundation. The registered enrollment target is 25 participants, below the 41-participant average among 7 other Hypertrophic Scar trials with a reported enrollment target (39% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04769089, a NA study of Hypertrophic Scar, has completed, sponsored by The Metis Foundation.

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

A prospective, double blind, randomized controlled human clinical trial will be conducted by enrolling patients referred for laser treatment from the USAISR burn clinic. Laser candidates will be asked to participate who have an area of extremity or truncal scar measuring approximately 6cmX6cm total, in one contiguous region. The study sites, will consist of four equally sized treatment areas (3cm x 3cm), will be randomized to be treated with PDL, CO2, a combination of CO2+PDL, and an untreated control for 6 treatments. The areas will be photographed prior to each treatment and at the final visit 4-6 months after the last treatment. Color, pliability and thickness will be measured using a colorimeter, cutometer and high frequency ultrasound respectively at each appointment. Additionally, the Patient Observer Scar Assessment Scale (POSAS) will be used to score the quality of the scar, using two trained, blinded observers. The patients will also be asked on a voluntary basis for a pre-trial and post-trial 3mm punch biopsy to evaluate for the presence of histological changes.

Conditions Studied

Interventions

  • OTHER Control
  • PROCEDURE Treatment with Pulse Dye Laser
  • PROCEDURE Treatment with CO2 Laser
  • PROCEDURE Treatment with combination of pulse dye laser and CO2 laser.

Study Locations (1)

Texas

  • United States Army Institute of Surgical Research - Fort Sam Houston

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2017-12-19
Est. Completion 2020-06-24
Phase NA

Sponsor

The Metis Foundation

8 total trials

What the Registry Record Tells You About NCT04769089

The ClinicalTrials.gov registry entry for NCT04769089 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 41-participant average among 7 other Hypertrophic Scar trials with a reported enrollment target (39% lower). The listed sponsor is The Metis Foundation, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hypertrophic Scar appearing as the primary indexed condition, and to 4 interventions - of which Control is the first listed.

NCT04769089 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT04769089 about?

NCT04769089 is a clinical study titled "Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars.". A prospective, double blind, randomized controlled human clinical trial will be conducted by enrolling patients referred for laser treatment from the USAISR burn clinic. Laser candidates will be asked to participate who have an area of extremity or truncal scar measuring approximately 6cmX6cm total,...

What is the current status of trial NCT04769089?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2017-12-19. Estimated completion is 2020-06-24.

What conditions does trial NCT04769089 study?

This clinical trial studies the following conditions: Hypertrophic Scar.

What interventions are being tested in trial NCT04769089?

The interventions under investigation include: Control (OTHER), Treatment with Pulse Dye Laser (PROCEDURE), Treatment with CO2 Laser (PROCEDURE), Treatment with combination of pulse dye laser and CO2 laser. (PROCEDURE).

Who is sponsoring clinical trial NCT04769089?

This trial is sponsored by The Metis Foundation, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04769089 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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