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NCT05478551 · ClinicalTrials.gov registry record · Phase 2

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

A Phase 2 study of Scar and Hypertrophic Scar, sponsored by Henry Ford Health System.

Active
Registry status
Phase 2
Development phase
12
Enrollment target
1
Study location

NCT05478551 is a Phase 2 study of Scar and Hypertrophic Scar that is active but no longer recruiting, run by Henry Ford Health System. The registered enrollment target is 12 participants, below the 48-participant average among 15 other Scar trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05478551, a Phase 2 study of Scar and Hypertrophic Scar, is active but no longer recruiting, sponsored by Henry Ford Health System.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The proposed study seeks to evaluate the scar reduction capacity of BTA on excision/biopsy wounds compared to the control (normal saline) in a double-blinded randomized control trial. It will expand upon previous studies that have already demonstrated the safety and good tolerance profile of BTA. We will be conducting a split-scar study/study involving two biopsy sites in a singular patient, allowing them to serve as their own control. In keeping with the results from previously conducted studies, we hypothesize that the wounds treated with BTA will have significantly less evidence of scar formation than those sites treated with normal saline.

Conditions Studied

Interventions

  • DRUG Normal saline
  • DRUG Botulinum Toxin

Study Locations (1)

Michigan

  • Henry Ford Health System - Detroit

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2022-06-01
Est. Completion 2026-12-30
Phase Phase 2

Sponsor

Henry Ford Health System

234 total trials

What the Registry Record Tells You About NCT05478551

The ClinicalTrials.gov registry entry for NCT05478551 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 48-participant average among 15 other Scar trials with a reported enrollment target (75% lower). The listed sponsor is Henry Ford Health System, which has 234 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Scar appearing as the primary indexed condition, and to 2 interventions - of which Normal saline is the first listed.

NCT05478551 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT05478551 about?

NCT05478551 is a clinical study titled "Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization". The proposed study seeks to evaluate the scar reduction capacity of BTA on excision/biopsy wounds compared to the control (normal saline) in a double-blinded randomized control trial. It will expand upon previous studies that have already demonstrated the safety and good tolerance profile of BTA. We...

What is the current status of trial NCT05478551?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2022-06-01. Estimated completion is 2026-12-30.

What conditions does trial NCT05478551 study?

This clinical trial studies the following conditions: Scar, Hypertrophic Scar.

What interventions are being tested in trial NCT05478551?

The interventions under investigation include: Normal saline (DRUG), Botulinum Toxin (DRUG).

Who is sponsoring clinical trial NCT05478551?

This trial is sponsored by Henry Ford Health System, which has 234 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05478551 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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