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Hereditary Angioedema (HAE): later-stage trial registry
4 of 8 indexed Hereditary Angioedema (HAE) trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 4 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Hereditary Angioedema (HAE): 8 US clinical trials tracked, 4 recruiting.
Hereditary Angioedema (HAE) is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Shire, running 2 of these trials.
Enrollment posture brief
Registry condition hereditary-angioedema-hae
OPEN 4 | RECR 50% | LATE 5 | EARLY 3 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Hereditary Angioedema (HAE) lists 4 open slots (50% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hereditary Angioedema (HAE) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hereditary Angioedema (HAE) is recruiting above its size-band peers.
4 of 8 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Hereditary Angioedema (HAE) research.
Shire accounts for 2 of 8 trials (25%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Hereditary Angioedema (HAE) trials plan to enrol fewer than 100 people.
Median target enrolment is 25 among the 8 trials that report a genuine target (sentinel values excluded). 6 of those (75%) plan for fewer than 100 participants.
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Hereditary Angioedema (HAE) research is mostly interventional.
8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
Pharvaris Netherlands B.V.
NCT06679881
A Study of Navenibart in Participants With Hereditary Angioedema
Astria Therapeutics
NCT06842823
Donidalorsen Treatment in Children With Hereditary Angioedema
Ionis Pharmaceuticals
NCT07298447
Oral Deucrictibant for Prophylactic and Acute Treatment in Hereditary Angioedema Patients
Institute for Asthma and Allergy
NCT07046806
Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
Pharvaris Netherlands B.V.
NCT06669754
A Phase 2 in Adult Subjects With Hereditary Angioedema
Shanghai Argo Biopharmaceutical Co.
NCT06846398
Safety and Efficacy Study of CINRYZE for Prevention of Angioedema Attacks in Children Ages 6-11 With Hereditary Angioedema
Shire
NCT02052141
CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12
Shire
NCT01095510
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on Hereditary Angioedema (HAE) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hereditary Angioedema (HAE) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hereditary Angioedema (HAE) page
8 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Hereditary Angioedema (HAE) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Shire sponsors the most Hereditary Angioedema (HAE) trials on record, review their full trial history before evaluating a specific study. See Shire's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hereditary Angioedema (HAE) condition card totals 8 registered trials; most-linked intervention Deucrictibant; top US site state Missouri. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.