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NCT06669754 · ClinicalTrials.gov registry record · Phase 3

Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

A Phase 3 study of Hereditary Angioedema (HAE), sponsored by Pharvaris Netherlands B.V..

Active
Registry status
Phase 3
Development phase
81
Enrollment target
20
Study locations

NCT06669754 is a Phase 3 study of Hereditary Angioedema (HAE) that is active but no longer recruiting, run by Pharvaris Netherlands B.V.. The registered enrollment target is 81 participants, above the 56-participant average among 7 other Hereditary Angioedema (HAE) trials with a reported enrollment target (45% higher). The trial reports 20 study locations across 5 states.

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The verdict

NCT06669754, a Phase 3 study of Hereditary Angioedema (HAE), is active but no longer recruiting, sponsored by Pharvaris Netherlands B.V..

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
81 participants
Enrollment target
20
Study locations

Study Summary

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of once-daily orally administered deucrictibant extended-release tablet compared to placebo for prophylaxis to prevent angioedema attacks in participants aged ≥ 12 years with hereditary angioedema.

Conditions Studied

Hereditary Angioedema (HAE)

Interventions

  • DRUG Placebo
  • DRUG Deucrictibant

Study Locations (20)

Other

  • Study Site - Corrientes
  • Study Site - San Martín
  • Study Site - Santo André
  • Study Site - Sofia
  • Study Site - Sofia
  • Study Site - Edmonton
  • Study Site - Ottawa
  • Study Site - Grenoble
  • Study Site - Lille
  • Study Site - Berlin
  • Study Site - Frankfurt
  • Study Site - Hanover
  • Study Site - Hong Kong
  • Study Site - Budapest

California

  • Study Site - San Diego
  • Study site - Santa Monica
  • Study site - Walnut Creek

Arkansas

  • Study Site - Little Rock

Maryland

  • Study Site - Chevy Chase

Missouri

  • Study Site - St Louis

Trial Details

FieldValue
Enrollment Target 81 participants
Start Date 2024-12-01
Est. Completion 2026-08
Phase Phase 3

Sponsor

Pharvaris Netherlands B.V.

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06669754

The ClinicalTrials.gov registry entry for NCT06669754 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 81 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 56-participant average among 7 other Hereditary Angioedema (HAE) trials with a reported enrollment target (45% higher). The listed sponsor is Pharvaris Netherlands B.V., which has 6 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hereditary Angioedema (HAE) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06669754 reports 20 study locations spanning 5 distinct geographic areas - top geographies include Other, California, Arkansas.

Frequently Asked Questions

What is clinical trial NCT06669754 about?

NCT06669754 is a clinical study titled "Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE". This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of once-daily orally administered deucrictibant extended-release tablet compared to placebo for prophylaxis to prevent angioedema attacks in participants aged ≥ 12 years with heredi...

What is the current status of trial NCT06669754?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 81 participants. The study started on 2024-12-01. Estimated completion is 2026-08.

What conditions does trial NCT06669754 study?

This clinical trial studies the following conditions: Hereditary Angioedema (HAE).

What interventions are being tested in trial NCT06669754?

The interventions under investigation include: Placebo (DRUG), Deucrictibant (DRUG).

Who is sponsoring clinical trial NCT06669754?

This trial is sponsored by Pharvaris Netherlands B.V., which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06669754 being conducted?

This trial has 20 study locations across Arkansas, California, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.