Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 3

Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

NCT06669754 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of once-daily orally administered deucrictibant extended-release tablet compared to placebo for prophylaxis to prevent angioedema attacks in participants aged ≥ 12 years with hereditary angioedema.

Interventions

  • DRUG Placebo
  • DRUG Deucrictibant

Study Locations (20)

Other

  • Study Site — Corrientes
  • Study Site — San Martín
  • Study Site — Santo André
  • Study Site — Sofia
  • Study Site — Sofia
  • Study Site — Edmonton
  • Study Site — Ottawa
  • Study Site — Grenoble
  • Study Site — Lille
  • Study Site — Berlin
  • Study Site — Frankfurt
  • Study Site — Hanover
  • Study Site — Hong Kong
  • Study Site — Budapest

California

  • Study Site — San Diego
  • Study site — Santa Monica
  • Study site — Walnut Creek

Arkansas

  • Study Site — Little Rock

Maryland

  • Study Site — Chevy Chase

Missouri

  • Study Site — St Louis

Trial Details

FieldValue
Enrollment Target 81 participants
Start Date 2024-12-01
Est. Completion 2026-08
Phase Phase 3

Sponsor

Pharvaris Netherlands B.V.

3 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06669754

The ClinicalTrials.gov registry entry for NCT06669754 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 81 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pharvaris Netherlands B.V., which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hereditary Angioedema (HAE) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06669754 reports 20 study locations spanning 5 distinct geographic areas — top geographies include Other, California, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06669754 about?

NCT06669754 is a clinical study titled "Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE". This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of once-daily orally administered deucrictibant extended-release tablet compared to placebo for prophylaxis to prevent angioedema attacks in participants aged ≥ 12 years with heredi...

What is the current status of trial NCT06669754?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 81 participants. The study started on 2024-12-01. Estimated completion is 2026-08.

What conditions does trial NCT06669754 study?

This clinical trial studies the following conditions: Hereditary Angioedema (HAE). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06669754?

The interventions under investigation include: Placebo (DRUG), Deucrictibant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06669754?

This trial is sponsored by Pharvaris Netherlands B.V., which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06669754 being conducted?

This trial has 20 study locations across Arkansas, California, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial