Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Gender Dysphoria: later-stage trial registry
5 of 9 indexed Gender Dysphoria trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 5 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Gender Dysphoria: 9 US clinical trials tracked, 5 recruiting.
Gender Dysphoria is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 2 of these trials.
Enrollment posture brief
Registry condition gender-dysphoria
OPEN 5 | RECR 56% | LATE 3 | EARLY 1 | RANK #1916 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Advanced Colorectal Cancer (56% recruiting · 9 trials)
Gender Dysphoria lists 5 open slots (56% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Gender Dysphoria on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Gender Dysphoria is recruiting above its size-band peers.
5 of 9 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Gender Dysphoria research.
University of Pittsburgh accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Gender Dysphoria enrolment sits around 90 participants.
Median target enrolment is 90 among the 9 trials that report a genuine target (sentinel values excluded). 5 of those (55.6%) plan for fewer than 100 participants.
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Gender Dysphoria splits between interventional and observational designs.
6 interventional and 3 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
Cedars-Sinai Medical Center
NCT04979338
Effect of Nitropaste in Chest Masculinizing Surgery
University of Virginia
NCT06428669
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
University of Colorado, Denver
NCT04596592
Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy
University of California, San Francisco
NCT07147166
Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy
Women and Infants Hospital of Rhode Island
NCT06969326
Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy
University of Pittsburgh
NCT05829928
Ovarian Tissue Cryopreservation in the Setting of Gender-affirming Therapy
University of Pittsburgh
NCT05863676
Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria
University of Wisconsin, Madison
NCT05884307
Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
Thomas Jefferson University
NCT04283656
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Gender Dysphoria records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Gender Dysphoria trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Gender Dysphoria page
9 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Gender Dysphoria trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Pittsburgh sponsors the most Gender Dysphoria trials on record, review their full trial history before evaluating a specific study. See University of Pittsburgh's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Gender Dysphoria condition card totals 9 registered trials; most-linked intervention Infectious Disease Testing; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.