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NCT05829928 · ClinicalTrials.gov registry record
Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy
A clinical trial of Gender Dysphoria and Transgender, sponsored by University of Pittsburgh.
- Active
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT05829928: Active study of Gender Dysphoria and Transgender, sponsored by University of Pittsburgh.
NCT05829928 is a study of Gender Dysphoria and Transgender that is active but no longer recruiting, run by University of Pittsburgh. The registered enrollment target is 150 participants, roughly in line with the 160-participant average among 8 other Gender Dysphoria trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05829928, a study of Gender Dysphoria and Transgender, is active but no longer recruiting, sponsored by University of Pittsburgh.
- ACTIVE NOT RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to: 1. Optimize techniques for processing and cryopreserving testicular tissue. 2. Determine presence and number of germ cells (sperm precursors) in the patients' testicular tissue. 3. Develop next generation cell- and tissue-based therapies for preserving fertility and treating infertility.
Primary Outcome
Testicular tissue will be used to isolate a suspension of testicular cells using a series of enzymatic digestions, washes, and filtrations. Testicular cells donated to the research pool will be frozen using varying cryopreservation methods and thawed to determine the efficacy of the freeze/thaw techniques. The concentration and number of recovered spermatogonial stem cells in the thawed cells will be determined using a human-to-nude mouse xenotransplantation assay. Recovery of spermatogonial ste
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Infectious Disease Testing
- PROCEDURE Gonadal Tissue Removal
Study Locations (1)
Pennsylvania
- Magee-Womens Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2019-05-09 |
| Est. Completion | 2029-05 |
What the registry record for NCT05829928 still lists
NCT05829928 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 160-participant average among 8 other Gender Dysphoria trials with a reported enrollment target.
The record links to 2 conditions, with Gender Dysphoria appearing as the primary indexed condition, and to 2 interventions - of which Infectious Disease Testing is the first listed.
NCT05829928 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05829928 about?
NCT05829928 is a clinical study titled "Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy". The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to: 1. Optimize techniques for processing and cryopreserving testicular tissue. 2. Determine presence and number of germ cells (sperm precursors) in the pat...
What is the current status of trial NCT05829928?
This trial is currently active not recruiting. The enrollment target is 150 participants. The study started on 2019-05-09. Estimated completion is 2029-05.
What conditions does trial NCT05829928 study?
This clinical trial studies the following conditions: Gender Dysphoria, Transgender.
What interventions are being tested in trial NCT05829928?
The interventions under investigation include: Infectious Disease Testing (DIAGNOSTIC_TEST), Gonadal Tissue Removal (PROCEDURE).
Who is sponsoring clinical trial NCT05829928?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05829928 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gender Dysphoria
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05829928's enrollment target sits among peer trials
150 3rd of 8 higher than 6 of 8 other Gender Dysphoria trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gender Dysphoria trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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