Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov official registry

Gastrointestinal Stromal Tumor clinical trials

All 9 indexed Gastrointestinal Stromal Tumor trials have closed enrollment.

9 US clinical trials ·

Gastrointestinal Stromal Tumor is the subject of 9 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 5 of these trials.

The research picture

Gastrointestinal Stromal Tumor has 9 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
5
top sponsor: National Cancer Institute (NCI)
Phase 12Phase 26

Active & Recent Trials

9 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2 38 participants

Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate

National Cancer Institute (NCI)

NCT00265798

COMPLETED NA 140 participants

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

Northwestern University

NCT01769248

COMPLETED Phase 2 100 participants

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

National Cancer Institute (NCI)

NCT00030667

COMPLETED Phase 2 89 participants

Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery

National Cancer Institute (NCI)

NCT00025246

COMPLETED Phase 2 55 participants

CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor

National Cancer Institute (NCI)

NCT00087074

COMPLETED Phase 2 45 participants

Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer

NYU Langone Health

NCT00005049

COMPLETED Phase 1 43 participants

Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer

National Cancer Institute (NCI)

NCT00397384

COMPLETED Phase 2 36 participants

Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery

Jonsson Comprehensive Cancer Center

NCT02880020

COMPLETED Phase 1 14 participants

Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST

Dana-Farber Cancer Institute

NCT02164240

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Gastrointestinal Stromal Tumor Trial Landscape

9 indexed Gastrointestinal Stromal Tumor studies · 0 recruiting (0%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: National Cancer Institute (NCI) (5 trials), 4 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Gastrointestinal Stromal Tumor?

PlainTrial tracks 9 US clinical trials for Gastrointestinal Stromal Tumor, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Gastrointestinal Stromal Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.