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NCT00265798 · ClinicalTrials.gov registry record · Phase 2

Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate

A Phase 2 study of Gastrointestinal Stromal Tumor, sponsored by National Cancer Institute (NCI).

Active
Registry status
Phase 2
Development phase
38
Enrollment target
6
Study locations

NCT00265798 is a Phase 2 study of Gastrointestinal Stromal Tumor that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 38 participants, below the 65-participant average among 8 other Gastrointestinal Stromal Tumor trials with a reported enrollment target (42% lower). The trial reports 6 study locations across 3 states.

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The verdict

NCT00265798, a Phase 2 study of Gastrointestinal Stromal Tumor, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
38 participants
Enrollment target
6
Study locations

Study Summary

This phase II trial is studying how well sorafenib works in treating patients with malignant gastrointestinal stromal tumor that progressed during or after previous treatment with imatinib mesylate and sunitinib malate. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.

Interventions

  • DRUG Sorafenib Tosylate

Study Locations (6)

Illinois

  • University of Chicago Comprehensive Cancer Center - Chicago
  • Decatur Memorial Hospital - Decatur
  • Central Illinois Hematology Oncology Center - Springfield

California

  • City of Hope Comprehensive Cancer Center - Duarte
  • University of California Davis Comprehensive Cancer Center - Sacramento

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2005-09-14
Est. Completion 2026-03-19
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00265798

The ClinicalTrials.gov registry entry for NCT00265798 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 65-participant average among 8 other Gastrointestinal Stromal Tumor trials with a reported enrollment target (42% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Gastrointestinal Stromal Tumor appearing as the primary indexed condition, and to 1 intervention - of which Sorafenib Tosylate is the first listed.

NCT00265798 reports 6 study locations spanning 3 distinct geographic areas - top geographies include Illinois, California, New York.

Frequently Asked Questions

What is clinical trial NCT00265798 about?

NCT00265798 is a clinical study titled "Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate". This phase II trial is studying how well sorafenib works in treating patients with malignant gastrointestinal stromal tumor that progressed during or after previous treatment with imatinib mesylate and sunitinib malate. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes nee...

What is the current status of trial NCT00265798?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 38 participants. The study started on 2005-09-14. Estimated completion is 2026-03-19.

What conditions does trial NCT00265798 study?

This clinical trial studies the following conditions: Gastrointestinal Stromal Tumor.

What interventions are being tested in trial NCT00265798?

The interventions under investigation include: Sorafenib Tosylate (DRUG).

Who is sponsoring clinical trial NCT00265798?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00265798 being conducted?

This trial has 6 study locations across California, Illinois, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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