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NCT00440388 · ClinicalTrials.gov registry record · Phase 2
Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma
A Phase 2 study of Follicular Lymphoma, sponsored by Ascenta Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 23
- Enrollment target
- 20
- Study locations
NCT00440388: Completed Phase 2 study of Follicular Lymphoma, sponsored by Ascenta Therapeutics.
NCT00440388 is a Phase 2 study of Follicular Lymphoma that has completed, run by Ascenta Therapeutics. The registered enrollment target is 23 participants, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (83% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00440388, a Phase 2 study of Follicular Lymphoma, has completed, sponsored by Ascenta Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 23 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a phase II clinical trial in patients who have not received systemic treatment for follicular non-Hodgkin's lymphoma. The study combines rituximab, an approved drug for this disease, with AT-101, an experimental drug. The hypothesis is that by adding AT-101 to the rituximab regimen, improvement to patients' response to the treatment will be observed verses rituximab alone.
Conditions Studied
Interventions
- DRUG Rituximab
- DRUG AT-101
Study Locations (20)
Texas
- Texas Oncology, P.A. - Bedford
- Texas Cancer Center at Medical City - Dallas
- Texas Oncology, P.A. - Fort Worth
- Allison Cancer Center - Midland
Florida
- Florida Cancer Institute - Hudson
- Florida Cancer Institute - New Port Richey
Alabama
- University of Alabama at Birmingham - Birmingham
Arizona
- Hematology Oncology Associates - Phoenix
Colorado
- Rocky Mountain Cancer Center-Aurora - Aurora
Illinois
- Cancer Care & Hematology Specialists of Chicagoland - Arlington Heights
Indiana
- Central Indiana Cancer Centers - Fishers
Michigan
- University of Michigan Cancer Center - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2006-10 |
| Est. Completion | 2008-11 |
| Phase | Phase 2 |
What the finished NCT00440388 record still lists
NCT00440388 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Follicular Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which Rituximab is the first listed.
NCT00440388 names 20 study sites across 16 states, led by Texas, Florida, Alabama.
Frequently Asked Questions
What is clinical trial NCT00440388 about?
NCT00440388 is a clinical study titled "Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma". This is a phase II clinical trial in patients who have not received systemic treatment for follicular non-Hodgkin's lymphoma. The study combines rituximab, an approved drug for this disease, with AT-101, an experimental drug. The hypothesis is that by adding AT-101 to the rituximab regimen, improvem...
What is the current status of trial NCT00440388?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2006-10. Estimated completion is 2008-11.
What conditions does trial NCT00440388 study?
This clinical trial studies the following conditions: Follicular Lymphoma.
What interventions are being tested in trial NCT00440388?
The interventions under investigation include: Rituximab (DRUG), AT-101 (DRUG).
Who is sponsoring clinical trial NCT00440388?
This trial is sponsored by Ascenta Therapeutics, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00440388 being conducted?
This trial has 20 study locations across Alabama, Arizona, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Follicular Lymphoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00440388's enrollment target sits among peer trials
23 79th of 89 higher than 11 of 89 other Follicular Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Follicular Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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