Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05551936 · ClinicalTrials.gov registry record · Phase 1
A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma
A Phase 1 study of Follicular Lymphoma, sponsored by Vaishalee Kenkre.
- Active
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
- 5
- Study locations
NCT05551936 is a Phase 1 study of Follicular Lymphoma that is active but no longer recruiting, run by Vaishalee Kenkre. The registered enrollment target is 42 participants, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (69% lower). The trial reports 5 study locations across 4 states.
The verdict
NCT05551936, a Phase 1 study of Follicular Lymphoma, is active but no longer recruiting, sponsored by Vaishalee Kenkre.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
- 5
- Study locations
Study Summary
This study is planned as a single arm clinical trial of tazemetostat in combination with bendamustine and rituximab with both a phase I and phase II component. All patients will receive tazemetostat twice daily on days 1-28 in combination with bendamustine 90 mg/m2 IV on days 1 and 2 and rituximab 375 mg/m2 IV on day 1 of a 28-day cycle for up to three cycles. Following this, patients will receive tazemetostat twice daily on days 1-28 and rituximab 375 mg/m2 IV on day 1 of a 28-day cycle for up to three cycles.
Conditions Studied
Interventions
- DRUG Rituximab
- DRUG Bendamustine
- DRUG Tazemetostat
Study Locations (5)
Illinois
- Northwestern University - Chicago
- University of Illinois Cancer Center - Chicago
New Jersey
- Rutgers Cancer Institute of New Jersey - New Brunswick
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Wisconsin
- University of Wisconsin Carbone Cancer Center - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2023-01-26 |
| Est. Completion | 2027-05 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05551936
The ClinicalTrials.gov registry entry for NCT05551936 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (69% lower). The listed sponsor is Vaishalee Kenkre, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Follicular Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Rituximab is the first listed.
NCT05551936 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Illinois, New Jersey, Ohio.
Frequently Asked Questions
What is clinical trial NCT05551936 about?
NCT05551936 is a clinical study titled "A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma". This study is planned as a single arm clinical trial of tazemetostat in combination with bendamustine and rituximab with both a phase I and phase II component. All patients will receive tazemetostat twice daily on days 1-28 in combination with bendamustine 90 mg/m2 IV on days 1 and 2 and rituximab 3...
What is the current status of trial NCT05551936?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2023-01-26. Estimated completion is 2027-05.
What conditions does trial NCT05551936 study?
This clinical trial studies the following conditions: Follicular Lymphoma.
What interventions are being tested in trial NCT05551936?
The interventions under investigation include: Rituximab (DRUG), Bendamustine (DRUG), Tazemetostat (DRUG).
Who is sponsoring clinical trial NCT05551936?
This trial is sponsored by Vaishalee Kenkre, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05551936 being conducted?
This trial has 5 study locations across Illinois, New Jersey, Ohio, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Follicular Lymphoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
RECRUITING · Phase 1
-
A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
RECRUITING · Phase 1
-
AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas
RECRUITING · Phase 1
-
CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
RECRUITING · Phase 1
-
CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies
RECRUITING · Phase 1
-
LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies
RECRUITING · Phase 1
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.