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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Edema: early-phase trial registry

5 of 14 indexed Edema trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 5 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Edema: 14 US clinical trials tracked, 5 recruiting.

Edema is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Church & Dwight Company, running 3 of these trials.

Enrollment posture brief

Registry condition edema

OPEN 5 | RECR 36% | LATE 1 | EARLY 3 | RANK #1230 | SPON 3

Nearest open-share peer: Attention (36% recruiting · 14 trials)

Edema (this)36%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Edema

Edema lists 5 open slots (36% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Edema on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Edema is recruiting below its size-band peers.

    5 of 14 indexed trials (35.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Edema research.

    Church & Dwight Company accounts for 3 of 14 trials (21.4%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Edema trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 14 trials that report a genuine target (sentinel values excluded). 9 of those (64.3%) plan for fewer than 100 participants.

  4. Edema research is mostly interventional.

    11 interventional and 3 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 22Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING 5,000 participants

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Duke University

NCT04278404

RECRUITING 150 participants

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

University of Michigan

NCT05505500

RECRUITING NA 60 participants

Surgical Evaluation for Upper Extremity Lymphedema (BioBridge)

Fibralign Corporation

NCT05695924

RECRUITING NA 60 participants

LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)

Fibralign Corporation

NCT04606030

RECRUITING NA 30 participants

Diuretic Tuner Clinical Decision Support

University of Texas Southwestern Medical Center

NCT04759274

ACTIVE NOT RECRUITING 166 participants

Screening For BCRL In Targeted Therapy For Breast Cancer

Massachusetts General Hospital

NCT05142800

ACTIVE NOT RECRUITING Phase 2 71 participants

Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy

M.D. Anderson Cancer Center

NCT02411656

ACTIVE NOT RECRUITING Phase 2 42 participants

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

M.D. Anderson Cancer Center

NCT02876107

COMPLETED NA 222 participants

Human Repeat Insult Patch Test to Evaluate Personal Lubricants

Church & Dwight Company

NCT02737631

COMPLETED NA 123 participants

Foot and Ankle Post-operative Oedema Management Using Geko™

Firstkind

NCT04927234

COMPLETED Phase 1 38 participants

Xerecept Intravenous Dose Escalation in Japanese and Caucasian Volunteers

Celtic Pharma Development Services

NCT00820092

COMPLETED NA 32 participants

A Single-Center, Clinical Study to Evaluate the Safety of a New Personal Lubricant in Healthy Female Subjects

Church & Dwight Company

NCT02737852

COMPLETED NA 30 participants

A Single-Center, Clinical Study to Evaluate the Safety of a Fragranced Personal Lubricant in Healthy Female Subjects

Church & Dwight Company

NCT02320214

COMPLETED Phase 4 20 participants

Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure

Sarfez Pharmaceuticals

NCT06995144

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 4 1

Named interventions

Most-linked intervention names on Edema records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Vascularized Lymph Node Transfer (VLNT) Procedure
2 trials
BioBridge® Collagen Matrix Device
2 trials
Laboratory Biomarker Analysis Other
2 trials
Immedate Release Torsemide Tablets Drug
1 trials
Extended Release Torsemide Tablets Drug
1 trials
Miami w/ frag Personal lubricant Device
1 trials
"Chameleon" Personal Lubricant Device
1 trials
geko™ therapy Device
1 trials

US sites by state

Facility locations filed on Edema trials. A trial with sites in several states counts in each.

Texas 4 trials
California 4 trials
New Jersey 3 trials
Massachusetts 2 trials
Illinois 2 trials
Florida 2 trials
Michigan 1 trials
Maryland 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Edema page

14 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Edema condition card totals 14 registered trials; most-linked intervention Vascularized Lymph Node Transfer (VLNT); top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.