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Pregnancy, High Risk: later-stage trial registry
13 of 21 indexed Pregnancy, High Risk trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #797 of 28,707 conditions by registered trial count.
21 US clinical trials · 13 currently recruiting · #797 of 28,707 conditions by registered trial count
Pregnancy, High Risk: 21 US clinical trials tracked, 13 recruiting.
Pregnancy, High Risk is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Ohio State University, running 5 of these trials.
Enrollment posture brief
Registry condition pregnancy-high-risk
OPEN 13 | RECR 62% | LATE 6 | EARLY 2 | RANK #797 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Rotator Cuff Tears (62% recruiting · 21 trials)
Pregnancy, High Risk lists 13 open slots (62% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pregnancy, High Risk on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pregnancy, High Risk is recruiting above its size-band peers.
13 of 21 indexed trials (61.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Pregnancy, High Risk research.
Ohio State University accounts for 5 of 21 trials (23.8%). 15 distinct sponsors appear on at least one study for this condition label.
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Typical Pregnancy, High Risk enrolment sits around 104 participants.
Median target enrolment is 104 among the 21 trials that report a genuine target (sentinel values excluded). 10 of those (47.6%) plan for fewer than 100 participants.
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Pregnancy, High Risk research is mostly interventional.
15 interventional and 6 observational studies make up this index (71.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
21 total, page 1 of 1
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Ohio State University
NCT06445946
Commercial or Open Source Closed Loop Impact on Pregnancy Study
University of California, San Francisco
NCT06654713
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Indiana University
NCT05124808
Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
Sumitomo Pharma Switzerland
NCT05739123
T1D Pregnancy & Me
Jaeb Center for Health Research
NCT06959316
Continuous Glucose Monitor Use in Pregnancy
University of Massachusetts, Worcester
NCT05317585
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Cedars-Sinai Medical Center
NCT05552053
Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching
Ohio State University
NCT05662462
A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE
Ohio State University
NCT05909046
Early Detection of Gestational Diabetes Mellitus in Pregnancy
University of Massachusetts, Worcester
NCT05388643
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Ohio State University
NCT06396078
Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)
Washington University School of Medicine
NCT05790252
Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
University of California, Irvine
NCT04861103
MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy
Sumitomo Pharma Switzerland
NCT05739136
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
University of Alabama at Birmingham
NCT04542148
Safer Conception Intervention for HIV-1 Serodiscordant Couples
University of Washington
NCT03030768
Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes Mellitus
Gianna Wilkie
NCT04599075
Daily Meditation Program in Women Admitted to the Antepartum Unit
The University of Texas Health Science Center, Houston
NCT03737279
Patient Versus Provider-led Titration of Insulin for Glycemic Control in Gestational Diabetes (EMPOWER)
Ohio State University
NCT05922033
MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study
Boston Medical Center
NCT03718104
A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women
University of Illinois at Chicago
NCT03646487
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on Pregnancy, High Risk records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pregnancy, High Risk trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pregnancy, High Risk page
21 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 13 Pregnancy, High Risk trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ohio State University sponsors the most Pregnancy, High Risk trials on record, review their full trial history before evaluating a specific study. See Ohio State University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pregnancy, High Risk condition card totals 21 registered trials; most-linked intervention Insulin; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.