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Diabetic Foot Ulcer clinical trials
42 of 68 indexed Diabetic Foot Ulcer trials are currently recruiting.
68 US clinical trials · 42 currently recruiting
Diabetic Foot Ulcer is the subject of 68 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Applied Biologics, running 3 of these trials.
The research picture
Diabetic Foot Ulcer has 68 registered US clinical trials, 42 of them open to new participants right now, about 62% of the total.
- 42
- recruiting participants now
- 62%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Applied Biologics
Active & Recent Trials
68 total, page 2 of 2
DermACELL in Subjects With Chronic Wounds of the Lower Extremities
LifeNet Health
NCT01970163
Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers
Aroa Biosurgery Limited
NCT06035536
Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care
ULURU
NCT05046158
VA MERIT: A Comparative Efficacy Study: Treatment of Non-Healing Diabetic
VA Office of Research and Development
NCT01450943
AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers
Integra LifeSciences Corporation
NCT03547635
Implementation of Telemedicine for Patient With Lower Extremity Wounds
University of California, Davis
NCT04440839
Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
Rion
NCT06319287
Diabetic Foot Ulcer (DFU) Rapid Pathogen Identification
University of Michigan
NCT06569238
Evaluation Of An Advanced Borderless Dressing
Smith & Nephew
NCT03146845
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Baylor College of Medicine
NCT03476876
The Effects of Nutrition Supplementation and Education on the Healing of Diabetic Foot Ulcer (DFU)
Florida State University
NCT04055064
Evaluating The Efficacy Of A Keratin Graft In Treating Non-Healing Diabetic Foot Ulcers
ProgenaCare Global
NCT05797285
Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
MiMedx Group
NCT01552499
Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers
Encoll
NCT06557122
Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft
Solsys Medical
NCT01676272
Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers
PluroGen Therapeutics
NCT02119754
Pilot Study of PHOENIX Wound Matrix® Impact on Chronic DFU Wound Microbiome
RenovoDerm
NCT04437537
Evaluating Clinical Acceptance of a NPWT Wound Care System
Medela
NCT03670225
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
| Phase 4 | 7 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetic Foot Ulcer Trial Landscape
68 indexed Diabetic Foot Ulcer studies · 42 recruiting (62%).
Phase mix: 9 late (III/IV) vs 8 early (I/II).
Top sponsor: Applied Biologics (3 trials), 9 others listed. 18 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetic Foot Ulcer?
PlainTrial tracks 68 US clinical trials for Diabetic Foot Ulcer, of which 42 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetic Foot Ulcer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.