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ClinicalTrials.gov 42 recruiting now full pipeline

Diabetic Foot Ulcer: full-pipeline trial registry

42 of 68 indexed Diabetic Foot Ulcer trials are currently recruiting.

Corpus placement: #203 of 28,707 conditions by registered trial count.

68 US clinical trials · 42 currently recruiting · #203 of 28,707 conditions by registered trial count

Diabetic Foot Ulcer: 68 US clinical trials tracked, 42 recruiting.

Diabetic Foot Ulcer is the subject of 68 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Applied Biologics, running 3 of these trials.

Enrollment posture brief

Registry condition diabetic-foot-ulcer

OPEN 42 | RECR 62% | LATE 9 | EARLY 8 | RANK #203 | SPON 3

Nearest open-share peer: Pregnancy, High Risk (62% recruiting · 21 trials)

Diabetic Foot Ulcer (this)62%Brain Metastases60.3%Refractory Multiple Myeloma33.8%Stress Disorders, Post-Traum29.4%Acne Vulgaris2.9%
Open-enrollment share among volume-matched conditions near Diabetic Foot Ulcer

Diabetic Foot Ulcer lists 42 open slots (62% of 68 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diabetic Foot Ulcer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diabetic Foot Ulcer is recruiting above its size-band peers.

    42 of 68 indexed trials (61.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Diabetic Foot Ulcer trials is spread across many organizations.

    Applied Biologics accounts for 3 of 68 trials (4.4%). 52 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diabetic Foot Ulcer enrolment sits around 120 participants.

    Median target enrolment is 120 among the 68 trials that report a genuine target (sentinel values excluded). 28 of those (41.2%) plan for fewer than 100 participants.

  4. Diabetic Foot Ulcer research is mostly interventional.

    61 interventional and 7 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 26Phase 32Phase 47

Open and recent trials

68 total, page 2 of 2

COMPLETED NA 202 participants

DermACELL in Subjects With Chronic Wounds of the Lower Extremities

LifeNet Health

NCT01970163

COMPLETED NA 143 participants

Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers

Aroa Biosurgery Limited

NCT06035536

COMPLETED NA 135 participants

Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care

ULURU

NCT05046158

COMPLETED Phase 3 120 participants

VA MERIT: A Comparative Efficacy Study: Treatment of Non-Healing Diabetic

VA Office of Research and Development

NCT01450943

COMPLETED NA 116 participants

AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers

Integra LifeSciences Corporation

NCT03547635

COMPLETED NA 116 participants

Implementation of Telemedicine for Patient With Lower Extremity Wounds

University of California, Davis

NCT04440839

COMPLETED Phase 2 59 participants

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

Rion

NCT06319287

COMPLETED NA 44 participants

Diabetic Foot Ulcer (DFU) Rapid Pathogen Identification

University of Michigan

NCT06569238

COMPLETED NA 40 participants

Evaluation Of An Advanced Borderless Dressing

Smith & Nephew

NCT03146845

COMPLETED Phase 2 34 participants

Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers

Baylor College of Medicine

NCT03476876

COMPLETED NA 29 participants

The Effects of Nutrition Supplementation and Education on the Healing of Diabetic Foot Ulcer (DFU)

Florida State University

NCT04055064

COMPLETED NA 26 participants

Evaluating The Efficacy Of A Keratin Graft In Treating Non-Healing Diabetic Foot Ulcers

ProgenaCare Global

NCT05797285

COMPLETED NA 25 participants

Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers

MiMedx Group

NCT01552499

COMPLETED NA 24 participants

Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers

Encoll

NCT06557122

COMPLETED 23 participants

Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft

Solsys Medical

NCT01676272

COMPLETED Phase 2 15 participants

Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers

PluroGen Therapeutics

NCT02119754

COMPLETED NA 11 participants

Pilot Study of PHOENIX Wound Matrix® Impact on Chronic DFU Wound Microbiome

RenovoDerm

NCT04437537

COMPLETED NA 10 participants

Evaluating Clinical Acceptance of a NPWT Wound Care System

Medela

NCT03670225

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 6
Phase 3 2
Phase 4 7

Named interventions

Most-linked intervention names on Diabetic Foot Ulcer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Standard of Care Other
7 trials
Standard of care Other
3 trials
Membrane Wrap-Hydro™ DFU Other
2 trials
Membrane Wrap-Lite™ DFU Other
2 trials
Membrane Wrap™ DFU Other
2 trials
Tri-Membrane Wrap™ DFU Other
2 trials
Standard of Care Procedure
2 trials
Standard of Care (SOC) Procedure
2 trials

US sites by state

Facility locations filed on Diabetic Foot Ulcer trials. A trial with sites in several states counts in each.

California 25 trials
Florida 22 trials
Texas 18 trials
Pennsylvania 18 trials
Ohio 9 trials
Illinois 9 trials
Virginia 8 trials
New York 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diabetic Foot Ulcer page

68 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 42 Diabetic Foot Ulcer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Applied Biologics sponsors the most Diabetic Foot Ulcer trials on record, review their full trial history before evaluating a specific study. See Applied Biologics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetic Foot Ulcer condition card totals 68 registered trials; most-linked intervention Standard of Care; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.