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Diabetic Foot
Open-data reference.
31 US clinical trials · 14 currently recruiting
Active & Recent Trials
A Real-World Registry of Chronic Wounds and Ulcers
U.S. Wound Registry
NCT02280733
DFC 004 Biomarkers for Active Diabetic Foot Ulcers
University of Michigan
NCT06104969
Effectiveness of Remote Foot Temperature Monitoring
VA Office of Research and Development
NCT05728411
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
BioLab Holdings
NCT07089602
Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence
University of Pittsburgh
NCT05172089
Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.
Tiger Biosciences
NCT06826339
Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
StimLabs
NCT06449638
Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs
MiMedx Group
NCT06600724
Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care
Applied Biologics
NCT06564831
Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers
Johns Hopkins University
NCT05579743
Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers
Axolotl Biologix
NCT06550596
A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
Applied Biologics
NCT07159282
Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers
University of Southern California
NCT06487780
Adapting Lifestyle Offloading for DFUs
University of Southern California
NCT06278935
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
Medaxis
NCT04564443
CGM and DFU Healing Post-discharge
Emory University
NCT06054659
SkinTE® for the Treatment of Wagner 1 Diabetic Foot Ulcers (COVER DFUS II)
PolarityTE
NCT06140303
Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM
BioStem Technologies
NCT06565156
Wound Assessment Using Spectral Imaging US
SpectralMD
NCT05415683
Thermal Screening for Early Diabetic Peripheral Neuropathy (DPN)
VisionQuest Biomedical
NCT03069729
Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers
Aroa Biosurgery Limited
NCT06035536
Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
Medical University of South Carolina
NCT02626156
Safety and Efficacy of ActiGraft Pro Compared to Standard of Care in DFUs
RedDress
NCT04185558
Implementation of Telemedicine for Patient With Lower Extremity Wounds
University of California, Davis
NCT04440839
Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers
LifeNet Health
NCT05087758
Safety and Efficacy Study of DSC127 in Treating Subjects With Diabetic Ulcers
US Biotest
NCT00796744
Monitoring Physiologic Parameters in Individuals With Diabetic Peripheral Neuropathy
Orpyx Medical Technologies
NCT05613556
The Association Between Unprotected Standing, Walking and Wound Healing in Diabetes
University of Arizona
NCT02233179
Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™
Aroa Biosurgery Limited
NCT06035523
Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU
Celularity Incorporated
NCT01859117
Study of Subjects With Diabetic Foot Ulcer (DFU)
GlaxoSmithKline
NCT03153007
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetic Foot Trial Landscape
ClinicalTrials.gov lists 31 US studies indexed under Diabetic Foot, and 14 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Diabetic Foot shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Diabetic Foot is led by Aroa Biosurgery Limited with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 31 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetic Foot?
PlainTrial tracks 31 US clinical trials for Diabetic Foot, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetic Foot?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.