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NCT05087758 · ClinicalTrials.gov registry record · NA
Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers
A NA study of Diabetic Foot and Lower Extremity Wound, sponsored by LifeNet Health.
- Completed
- Registry status
- NA
- Development phase
- 108
- Enrollment target
- 8
- Study locations
NCT05087758: Completed NA study of Diabetic Foot and Lower Extremity Wound, sponsored by LifeNet Health.
NCT05087758 is a NA study of Diabetic Foot and Lower Extremity Wound that has completed, run by LifeNet Health. The registered enrollment target is 108 participants, below the 10,338-participant average among 30 other Diabetic Foot trials with a reported enrollment target (99% lower). The trial reports 8 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05087758, a NA study of Diabetic Foot and Lower Extremity Wound, has completed, sponsored by LifeNet Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 108 participants
- Enrollment target
- 8
- Study locations
Study Summary
In this study, a novel placental membrane product Matrion™ (LifeNet Health, Inc., Virginia Beach, VA) will be used as a treatment for subjects with diabetic foot ulcers. Matrion is composed of placental membrane derived from donated human birth tissue containing both the innermost amniotic layer and the outermost chorionic layer, inclusive of the trophoblast layer. Matrion is minimally processed and disinfected using a proprietary decellularization technology and terminally sterilized that safely renders the placental membrane acellular and sterile for its intended surgical applications.
Primary Outcome
Proportion of chronic DFUs that have achieved complete wound closure
Conditions Studied
Interventions
- OTHER Matrion
- OTHER Conventional Care Wound Management
Study Locations (8)
California
- Center for Clinical Research, INC - Carmichael
- Limb Preservation Platform, INC - Fresno
- ILD Research Center - San Diego
- Center for Clinical Research, INC - San Francisco
Arizona
- Compass Medical Research Center, LLC - Tucson
Florida
- Doctors Research Network - Miami
New Mexico
- Albuquerque Associated Podiatrists - Albuquerque
North Carolina
- Purvis-Moyer Foot and Ankle Center - Rocky Mount
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2022-03-01 |
| Est. Completion | 2025-02-28 |
| Phase | NA |
What the finished NCT05087758 record still lists
NCT05087758 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 10,338-participant average among 30 other Diabetic Foot trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Diabetic Foot appearing as the primary indexed condition, and to 2 interventions - of which Matrion is the first listed.
NCT05087758 lists 8 locations in 5 states (California, Arizona, Florida).
Frequently Asked Questions
What is clinical trial NCT05087758 about?
NCT05087758 is a clinical study titled "Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers". In this study, a novel placental membrane product Matrion™ (LifeNet Health, Inc., Virginia Beach, VA) will be used as a treatment for subjects with diabetic foot ulcers. Matrion is composed of placental membrane derived from donated human birth tissue containing both the innermost amniotic layer and...
What is the current status of trial NCT05087758?
This trial is currently completed. It is a NA study. The enrollment target is 108 participants. The study started on 2022-03-01. Estimated completion is 2025-02-28.
What conditions does trial NCT05087758 study?
This clinical trial studies the following conditions: Diabetic Foot, Lower Extremity Wound.
What interventions are being tested in trial NCT05087758?
The interventions under investigation include: Matrion (OTHER), Conventional Care Wound Management (OTHER).
Who is sponsoring clinical trial NCT05087758?
This trial is sponsored by LifeNet Health, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05087758 being conducted?
This trial has 8 study locations across Arizona, California, Florida, New Mexico, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetic Foot
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05087758's enrollment target sits among peer trials
108 19th of 30 higher than 12 of 30 other Diabetic Foot trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetic Foot trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers
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-
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Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs
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Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care
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Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers
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-
Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
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