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Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence
NCT05172089 · View on ClinicalTrials.gov ↗
Study Summary
This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function. ii) whether such functionally deficient wound closure, manifested as high TEWL, is associated with greater wound recurrence. The primary parent study will also address molecular mechanisms implicated in biofilm-induced loss of skin epithelial barrier integrity in DFU patients.
Conditions Studied
Study Locations (2)
Arizona
- University of Arizona — Tucson
Pennsylvania
- UPMC Wound Healing Services at UPMC Passavant — Cranberry Township
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 405 participants |
| Start Date | 2024-04-02 |
| Est. Completion | 2029-06-27 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05172089
The ClinicalTrials.gov registry entry for NCT05172089 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 405 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,082 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Diabetic Foot appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05172089 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Arizona, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05172089 about?
NCT05172089 is a clinical study titled "Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence". This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function. ii) whether such functionally deficient wound closure, manifested as high TEWL, is associated with greater wound recurrenc...
What is the current status of trial NCT05172089?
This trial is currently recruiting. The enrollment target is 405 participants. The study started on 2024-04-02. Estimated completion is 2029-06-27.
What conditions does trial NCT05172089 study?
This clinical trial studies the following conditions: Diabetic Foot, Diabetic Foot Infection, Chronic Wounds, Biofilm Infection, Trans-epidermal Water Loss (TEWL). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05172089?
This trial is sponsored by University of Pittsburgh, which has 1,082 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05172089 being conducted?
This trial has 2 study locations across Arizona, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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