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NCT05172089 · ClinicalTrials.gov registry record
Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence
A clinical trial of Diabetic Foot and Diabetic Foot Infection, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- 405
- Enrollment target
- 2
- Study locations
NCT05172089: Recruiting study of Diabetic Foot and Diabetic Foot Infection, sponsored by University of Pittsburgh.
NCT05172089 is a study of Diabetic Foot and Diabetic Foot Infection that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 405 participants, below the 10,328-participant average among 30 other Diabetic Foot trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05172089, a study of Diabetic Foot and Diabetic Foot Infection, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- 405 participants
- Enrollment target
- 2
- Study locations
Study Summary
This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function. ii) whether such functionally deficient wound closure, manifested as high TEWL, is associated with greater wound recurrence. The primary parent study will also address molecular mechanisms implicated in biofilm-induced loss of skin epithelial barrier integrity in DFU patients.
Primary Outcome
Test the incidence of wound biofilm infection at initial visit and test its association with deficient skin barrier function at the closed DFU-site
Conditions Studied
Study Locations (2)
Arizona
- University of Arizona - Tucson
Pennsylvania
- UPMC Wound Healing Services at UPMC Passavant - Cranberry Township
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 405 participants |
| Start Date | 2024-04-02 |
| Est. Completion | 2029-06-27 |
What NCT05172089 shows while recruiting
NCT05172089 is an observational study that tracks outcomes without assigning an intervention. The registered 405 participants enrollment target is mid-sized for trials with a published cap, below the 10,328-participant average among 30 other Diabetic Foot trials with a reported enrollment target (96% lower).
The record links to 5 conditions, with Diabetic Foot appearing as the primary indexed condition, and to 0 interventions.
NCT05172089 reports a single indexed study location in Arizona, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05172089 about?
NCT05172089 is a clinical study titled "Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence". This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function. ii) whether such functionally deficient wound closure, manifested as high TEWL, is associated with greater wound recurrenc...
What is the current status of trial NCT05172089?
This trial is currently recruiting. The enrollment target is 405 participants. The study started on 2024-04-02. Estimated completion is 2029-06-27.
What conditions does trial NCT05172089 study?
This clinical trial studies the following conditions: Diabetic Foot, Diabetic Foot Infection, Chronic Wounds, Biofilm Infection, Trans-epidermal Water Loss (TEWL).
Who is sponsoring clinical trial NCT05172089?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05172089 being conducted?
This trial has 2 study locations across Arizona, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetic Foot
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05172089's enrollment target sits among peer trials
405 5th of 30 higher than 26 of 30 other Diabetic Foot trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetic Foot trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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