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ClinicalTrials.gov official registry

Dengue clinical trials

All 10 indexed Dengue trials have closed enrollment.

10 US clinical trials ·

Dengue is the subject of 10 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 6 of these trials.

The research picture

Dengue has 10 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
6
top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase 17Phase 21

Active & Recent Trials

10 total, page 1 of 1

COMPLETED 35,035 participants

Procleix® Dengue Virus Assay Testing of Individual Donor Samples From Puerto Rican Blood Donors - American Red Cross

Gen-Probe, Incorporated

NCT01656174

COMPLETED Phase 2 390 participants

Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine

Sanofi Pasteur, a Sanofi Company

NCT01488890

COMPLETED NA 95 participants

Defining Skin Immunity of a Bite of Key Insect Vectors in Humans

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03641339

COMPLETED Phase 1 80 participants

TDENV PIV and LAV Dengue Prime-boost Strategy

U.S. Army Medical Research and Development Command

NCT02239614

COMPLETED Phase 1 72 participants

Tetravalent Chimeric Dengue Vaccine Trial

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01110551

COMPLETED Phase 1 58 participants

Evaluating the Safety and Immune Response to Two Admixtures of a Tetravalent Dengue Virus Vaccine

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01506570

COMPLETED Phase 1 48 participants

Evaluation of the Safety and Efficacy of a Single Dose of a Dengue Vaccine (TV005) in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02317900

COMPLETED Phase 1 29 participants

Safety of and Immune Response to a Dengue Virus Vaccine (rDEN3-3'Ddelta30) in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00712803

COMPLETED Phase 1 12 participants

Evaluating the Clinical and Immune Response to Two Dengue Virus Vaccines in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02392325

COMPLETED Phase 1 10 participants

ADVP005; Dengue CVD 12000 - Dengue-1-Virus Live Virus Human Challenge (DENV-1-LVHC)

University of Maryland, Baltimore

NCT04786457

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dengue Trial Landscape

10 indexed Dengue studies · 0 recruiting (0%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (6 trials), 4 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dengue?

PlainTrial tracks 10 US clinical trials for Dengue, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dengue?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.