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NCT04786457 · ClinicalTrials.gov registry record · Phase 1
ADVP005; Dengue CVD 12000 - Dengue-1-Virus Live Virus Human Challenge (DENV-1-LVHC)
A Phase 1 study of Dengue, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT04786457 is a Phase 1 study of Dengue that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 10 participants, below the 3,980-participant average among 9 other Dengue trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04786457, a Phase 1 study of Dengue, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to test the protection of volunteers previously vaccinated with Tetravalent Dengue Virus (TDEN) Purified Inactivated Vaccine (PIV) with alum and boosted with TDEN live attenuated vaccine (LAV) formulation against a weakened form of an experimental dengue virus challenge. The Investigators will also include people that have not received the study vaccine. The Investigators are collecting information about how the vaccine protects against a dengue virus challenge as well as adding to knowledge about the safety of the challenge.
Conditions Studied
Interventions
- BIOLOGICAL Dengue 1 Live Virus Human Challenge (DENV-1-LVHC)
Study Locations (1)
Maryland
- University of Maryland, Baltimore, Center for Vaccine Development and Global Health - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2020-11-30 |
| Est. Completion | 2021-07-09 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04786457
The ClinicalTrials.gov registry entry for NCT04786457 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,980-participant average among 9 other Dengue trials with a reported enrollment target (100% lower). The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Dengue appearing as the primary indexed condition, and to 1 intervention - of which Dengue 1 Live Virus Human Challenge (DENV-1-LVHC) is the first listed.
NCT04786457 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04786457 about?
NCT04786457 is a clinical study titled "ADVP005; Dengue CVD 12000 - Dengue-1-Virus Live Virus Human Challenge (DENV-1-LVHC)". The purpose of this research study is to test the protection of volunteers previously vaccinated with Tetravalent Dengue Virus (TDEN) Purified Inactivated Vaccine (PIV) with alum and boosted with TDEN live attenuated vaccine (LAV) formulation against a weakened form of an experimental dengue virus c...
What is the current status of trial NCT04786457?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2020-11-30. Estimated completion is 2021-07-09.
What conditions does trial NCT04786457 study?
This clinical trial studies the following conditions: Dengue.
What interventions are being tested in trial NCT04786457?
The interventions under investigation include: Dengue 1 Live Virus Human Challenge (DENV-1-LVHC) (BIOLOGICAL).
Who is sponsoring clinical trial NCT04786457?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04786457 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.