U.S. Army Medical Research and Development Command

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, U.S. Army Medical Research and Development Command sits in the top decile of US sponsors by registered trial count (#284 of 15,742 sponsors by registered trial count).

77 total trials 3 currently recruiting 71 completed early-phase tilt top decile by trial count

U.S. Army Medical Research and Development Command: 77 sponsored US clinical trials, 3 recruiting.

U.S. Army Medical Research and Development Command sponsors 77 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 71 completed. 0 of these trials are in Phase 3-4 (later-stage) and 70 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Malaria, with 6 trials.

Top-decile sponsor footprint

U.S. Army Medical Research and Development Command ranks in the top decile of sponsors by registered trial count (#284 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 83/100

71 of 73 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (97.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

77 total, page 1 of 2

RECRUITING

An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

NCT04180930

RECRUITING Phase 2

Phase 2 Safety and Immunogenicity Study of Rift Valley Fever Vaccine

NCT03609398

RECRUITING NA

Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep

NCT02945501

COMPLETED Phase 1

Safety, Tolerability, and Immunogenicity of ALFQ in a HIV Vaccine Containing A244 and B.65321 in Healthy Adults

NCT05423418

COMPLETED Phase 2

Single or Repeat Dose of G03-52-01 in Adult Subjects

NCT05348993

COMPLETED Phase 2

Safety/Immunogenicity Hantaan Virus DNA Vaccine and Puumala Virus DNA Vaccine, For Prevention of HFRS

NCT04333459

NOT YET RECRUITING Phase 2

Safety and Immunogenicity Study of Venezuelan Equine Encephalomyelitis (VEE) Vaccine as Booster Vaccine in Adults

NCT03531242

COMPLETED Phase 1

PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19

NCT04784767

COMPLETED Phase 1

Combination HTNV and PUUV DNA Vaccine

NCT03718130

COMPLETED Phase 1

Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54

NCT03882528

COMPLETED Phase 1

Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults

NCT03341754

COMPLETED Early Phase 1

Study Assessing Pharmacokinetics and Bioavailability of Three Novel Triazine Compounds

NCT03436160

COMPLETED Phase 1

Ascending Doses of Autologous FDP vs FFP

NCT02930226

COMPLETED Phase 1

A Single-blind Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Hantaan Puumala Virus DNA Vaccine

NCT02776761

COMPLETED Phase 1

Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR)

NCT02445963

COMPLETED Phase 1

Assessment of a Dengue-1-Virus-Live Virus Human Challenge - (DENV-1-LVHC) Virus Strain

NCT02372175

COMPLETED Phase 1

Study of Varying Injection Schedules of TDENV-PIV Vaccine With AS03B Adjuvant and Placebo in Healthy US Adults

NCT02421367

COMPLETED Phase 1

TDENV PIV and LAV Dengue Prime-boost Strategy

NCT02239614

COMPLETED Phase 1

Phase 1 Safety Study of Dimethyl Sulfoxide Cryopreserved Platelets

NCT02078284

COMPLETED Phase 1

Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults

NCT02174978

COMPLETED Phase 2

Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever

NCT02116205

COMPLETED Phase 1

Safety Study of a Capsule-Conjugate Vaccine to Prevent Campylobacter-Caused Diarrhea

NCT02067676

COMPLETED Phase 1

Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population

NCT01877421

COMPLETED Phase 1

Immunization Via Mosquito Bite With Radiation-attenuated Sporozoites

NCT01994525

COMPLETED Phase 2

Challenge Study of an ETEC Vaccine

NCT01922856

TERMINATED Phase 2

Safety, Efficacy, and PK of Topical Paromomycin/Gentamicin Cream for Treatment of Cutaneous Leishmaniasis

NCT01140191

COMPLETED

Evaluation of CL Detect™ Rapid Test to Detect Cutaneous Leishmaniasis

NCT01865032

COMPLETED Phase 1

Booster Dose (50 µg) of Recombinant Ricin Toxin Vaccine (RVEc™) in Previously Vaccinated Healthy Adults

NCT01846104

COMPLETED Phase 2

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

NCT01611194

COMPLETED Phase 1

A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy Adults

NCT01666652

COMPLETED Phase 1

Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea

NCT01644565

COMPLETED Phase 1

Study to Evaluate the Safety of a New Oxime, MMB4 DIMETHANESULFONATE (DMS)

NCT02018250

COMPLETED Phase 1

Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults

NCT01540474

COMPLETED

Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance

NCT01194336

COMPLETED Phase 1

Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA Vaccines

NCT01502345

COMPLETED Phase 1

Evaluation of the Safety and the Ability of a DNA Vaccine to Protect Against Dengue Disease

NCT01502358

COMPLETED Phase 1

Safety Study of a Vaccine (DENV-1 PIV) to Prevent Dengue Disease

NCT01502735

COMPLETED Phase 1

Safety Study of Recombinant Vaccine to Prevent ETEC Diarrhea

NCT01382095

COMPLETED

Reference Values for Non-invasive Hydration Status Markers H10-14

NCT01387529

COMPLETED Phase 1

Safety and Immunogenicity Study of Recombinant Ricin Toxin A-Chain Vaccine (RVEc™)

NCT01317667

COMPLETED Phase 2

Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)

NCT01306968

COMPLETED Phase 1

Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults

NCT01157897

COMPLETED Phase 1

Western Equine Encephalitis Vaccine, Inactivated

NCT01159561

COMPLETED Phase 2

Weekly Dosing of Malarone ® for Prevention of Malaria

NCT00984256

COMPLETED Phase 2

Safety and Immunogenicity Study of Rift Valley Fever Vaccine, Inactivated

NCT00869713

COMPLETED Phase 1

Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria

NCT00870987

COMPLETED Phase 1

Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans

NCT00935623

COMPLETED NA

Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria Infection

NCT00761020

COMPLETED Phase 2

Safety and Immunogenicity Study of Eastern Equine Encephalitis (EEE) Vaccine

NCT00584805

COMPLETED Phase 2

Safety and Immunogenicity Study of the Eastern Equine Encephalitis (EEE) Vaccine

NCT02654509

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What is open in the U.S. Army Medical Research and Development Command pipeline

3 recruiting of 77 indexed (4% open); 71 completed (92%).

Phase mix: 0 late (III/IV) vs 70 early (I/II) (early-phase heavy).

Top condition: Malaria (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

U.S. Army Medical Research and Development Command: open-pipeline peers nationwide

Peers matched on 77 registered trials and 4% open enrollment, not the therapeutic-area sidebar.

U.S. Army Medical Research and Development Command sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400 0%5%10%15%20% Total trials Recruiting share U.S. Army Medical Research and Development CommandUniversity of HawaiiRANDIonis PharmaceuticalsMetroHealth Medical CenterCelgeneMedtronicNeuroAldeyra TherapeuticsDexCom
U.S. Army Medical Research and Development Command sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

U.S. Army Medical Research and Development Command sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 77 trials (± recruiting share)

Sponsors near 4% open enrollment (± trial volume)

What to do with this U.S. Army Medical Research and Development Command page

77 registered trials is a research-attention snapshot, not an endorsement of U.S. Army Medical Research and Development Command or any single study.

  • 3 of U.S. Army Medical Research and Development Command's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Malaria is the condition U.S. Army Medical Research and Development Command studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Malaria trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

U.S. Army Medical Research and Development Command pipeline card: 77 registered trials from official public datasets.Report a data error.