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NCT02239614 · ClinicalTrials.gov registry record · Phase 1

TDENV PIV and LAV Dengue Prime-boost Strategy

A Phase 1 study of Dengue, sponsored by U.S. Army Medical Research and Development Command.

Completed
Registry status
Phase 1
Development phase
80
Enrollment target
1
Study location

NCT02239614 is a Phase 1 study of Dengue that has completed, run by U.S. Army Medical Research and Development Command. The registered enrollment target is 80 participants, below the 3,972-participant average among 9 other Dengue trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02239614, a Phase 1 study of Dengue, has completed, sponsored by U.S. Army Medical Research and Development Command.

COMPLETED
Registry status
Phase 1
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

The potential synergistic effect of administering 2 dengue vaccine candidates that were previously shown to be safe and immunogenic in humans will be evaluated in this study. A prime-boost study of tetravalent dengue virus purified inactivated vaccine (TDENV-PIV) with alum and tetravalent dengue live attenuated virus (TDENV-LAV) vaccine Formulation 17 (F17) will gather data to help better understand the human immune response to dengue vaccination and infection.

Conditions Studied

Interventions

  • BIOLOGICAL TDENV-LAV
  • BIOLOGICAL TDENV-PIV 4 µg + alum adjuvant

Study Locations (1)

Maryland

  • Clinical Trials Center, Walter Reed Army Institute of Research (CTC, WRAIR) - Silver Spring

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2014-12
Est. Completion 2017-02-17
Phase Phase 1

What the Registry Record Tells You About NCT02239614

The ClinicalTrials.gov registry entry for NCT02239614 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,972-participant average among 9 other Dengue trials with a reported enrollment target (98% lower). The listed sponsor is U.S. Army Medical Research and Development Command, which has 77 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Dengue appearing as the primary indexed condition, and to 2 interventions - of which TDENV-LAV is the first listed.

NCT02239614 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT02239614 about?

NCT02239614 is a clinical study titled "TDENV PIV and LAV Dengue Prime-boost Strategy". The potential synergistic effect of administering 2 dengue vaccine candidates that were previously shown to be safe and immunogenic in humans will be evaluated in this study. A prime-boost study of tetravalent dengue virus purified inactivated vaccine (TDENV-PIV) with alum and tetravalent dengue liv...

What is the current status of trial NCT02239614?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2014-12. Estimated completion is 2017-02-17.

What conditions does trial NCT02239614 study?

This clinical trial studies the following conditions: Dengue.

What interventions are being tested in trial NCT02239614?

The interventions under investigation include: TDENV-LAV (BIOLOGICAL), TDENV-PIV 4 µg + alum adjuvant (BIOLOGICAL).

Who is sponsoring clinical trial NCT02239614?

This trial is sponsored by U.S. Army Medical Research and Development Command, which has 77 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02239614 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.