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NCT02392325 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Clinical and Immune Response to Two Dengue Virus Vaccines in Healthy Adults

A Phase 1 study of Dengue, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT02392325 is a Phase 1 study of Dengue that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 12 participants, below the 3,980-participant average among 9 other Dengue trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02392325, a Phase 1 study of Dengue, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Dengue viruses infect millions of people throughout the tropics and subtropics each year. The development of a dengue vaccine is an important health priority. This study will evaluate the immunologic and clinical response to two dengue vaccines, given 9 months apart, in healthy adults with no history of previous flavivirus infection.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL rDEN1Δ30
  • BIOLOGICAL rDEN2Δ30-7169

Study Locations (1)

Maryland

  • Center for Immunization Research, Johns Hopkins School of Public Health - Baltimore

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2015-03
Est. Completion 2017-02
Phase Phase 1

What the Registry Record Tells You About NCT02392325

The ClinicalTrials.gov registry entry for NCT02392325 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,980-participant average among 9 other Dengue trials with a reported enrollment target (100% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Dengue appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT02392325 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT02392325 about?

NCT02392325 is a clinical study titled "Evaluating the Clinical and Immune Response to Two Dengue Virus Vaccines in Healthy Adults". Dengue viruses infect millions of people throughout the tropics and subtropics each year. The development of a dengue vaccine is an important health priority. This study will evaluate the immunologic and clinical response to two dengue vaccines, given 9 months apart, in healthy adults with no histor...

What is the current status of trial NCT02392325?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2015-03. Estimated completion is 2017-02.

What conditions does trial NCT02392325 study?

This clinical trial studies the following conditions: Dengue.

What interventions are being tested in trial NCT02392325?

The interventions under investigation include: Placebo (BIOLOGICAL), rDEN1Δ30 (BIOLOGICAL), rDEN2Δ30-7169 (BIOLOGICAL).

Who is sponsoring clinical trial NCT02392325?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02392325 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.