Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cushing Syndrome: early-phase trial registry
5 of 10 indexed Cushing Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Cushing Syndrome: 10 US clinical trials tracked, 5 recruiting.
Cushing Syndrome is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Corcept Therapeutics, running 3 of these trials.
Enrollment posture brief
Registry condition cushing-syndrome
OPEN 5 | RECR 50% | LATE 2 | EARLY 6 | RANK #1724 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Cushing Syndrome lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cushing Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cushing Syndrome is recruiting above its size-band peers.
5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Cushing Syndrome research.
Corcept Therapeutics accounts for 3 of 10 trials (30%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Cushing Syndrome enrolment sits around 125 participants.
Median target enrolment is 125 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.
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Cushing Syndrome research is mostly interventional.
8 interventional and 2 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
Mayo Clinic
NCT04543253
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Memorial Sloan Kettering Cancer Center
NCT03364803
Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06635629
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
Crinetics Pharmaceuticals
NCT05804669
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome
Recordati Group
NCT03708900
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
Corcept Therapeutics
NCT03604198
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
Corcept Therapeutics
NCT03697109
New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001849
Open-label Treatment in Cushing's Syndrome
Cortendo AB
NCT03621280
Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
Corcept Therapeutics
NCT05347979
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Cushing Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cushing Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cushing Syndrome page
10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Cushing Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Corcept Therapeutics sponsors the most Cushing Syndrome trials on record, review their full trial history before evaluating a specific study. See Corcept Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cushing Syndrome condition card totals 10 registered trials; most-linked intervention Relacorilant; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.