Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cushing Syndrome clinical trials
Every US clinical trial registered for Cushing Syndrome — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
10 US clinical trials · 5 currently recruiting
The research picture
Cushing Syndrome has 10 registered US clinical trials, 5 of them open to new participants right now — about 50% of the total.
- 5
- recruiting participants now
- 50%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Corcept Therapeutics
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
Mayo Clinic
NCT04543253
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Memorial Sloan Kettering Cancer Center
NCT03364803
Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06635629
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
Crinetics Pharmaceuticals
NCT05804669
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome
RECORDATI GROUP
NCT03708900
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
Corcept Therapeutics
NCT03604198
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
Corcept Therapeutics
NCT03697109
New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001849
Open-label Treatment in Cushing's Syndrome
Cortendo AB
NCT03621280
Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
Corcept Therapeutics
NCT05347979
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cushing Syndrome Trial Landscape
ClinicalTrials.gov lists 10 US studies indexed under Cushing Syndrome, and 5 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cushing Syndrome shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cushing Syndrome is led by Corcept Therapeutics with 3 indexed trials, alongside 7 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cushing Syndrome?
PlainTrial tracks 10 US clinical trials for Cushing Syndrome, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cushing Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.