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Crohn Disease: early-phase trial registry
34 of 72 indexed Crohn Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #191 of 28,707 conditions by registered trial count.
72 US clinical trials · 34 currently recruiting · #191 of 28,707 conditions by registered trial count
Crohn Disease: 72 US clinical trials tracked, 34 recruiting.
Crohn Disease is the subject of 72 registered US clinical trials on ClinicalTrials.gov, 34 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 20 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 6 of these trials.
Enrollment posture brief
Registry condition crohn-disease
OPEN 34 | RECR 47% | LATE 13 | EARLY 20 | RANK #191 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Psychosis (47% recruiting · 36 trials)
Crohn Disease lists 34 open slots (47% of 72 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Crohn Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Crohn Disease is recruiting above its size-band peers.
34 of 72 indexed trials (47.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Crohn Disease trials is spread across many organizations.
Massachusetts General Hospital accounts for 6 of 72 trials (8.3%). 51 distinct sponsors appear on at least one study for this condition label.
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Typical Crohn Disease enrolment sits around 84 participants.
Median target enrolment is 84 among the 72 trials that report a genuine target (sentinel values excluded). 38 of those (52.8%) plan for fewer than 100 participants.
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Crohn Disease research is mostly interventional.
58 interventional and 14 observational studies make up this index (80.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
72 total, page 2 of 2
Safety and Efficacy of Adalimumab Versus Ustekinumab for One Year
Janssen Scientific Affairs
NCT03464136
A Study to Test the Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
Teva Branded Pharmaceutical Products R&D
NCT05499130
Clinical Study Comparing PillCam® Crohn's Capsule Endoscopy to Ileocolonoscopy (IC) Plus MRE for Detection of Active CD in the Small Bowel and Colon in Subjects With Known CD and Mucosal Disease.
Medtronic - MITG
NCT03241368
BI 695501 Versus Humira in Patients With Active Crohn's Disease: a Trial Comparing Efficacy, Endoscopic Improvement, Safety, and Immunogenicity
Boehringer Ingelheim
NCT02871635
Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)
Cedars-Sinai Medical Center
NCT03723447
Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System
Capso Vision
NCT04573959
Pneumococcal Vaccination in Patients With Inflammatory Bowel Disease
Cedars-Sinai Medical Center
NCT00829595
A Randomized, Double-blind, Study to Explore the Effect of GED-0301 in Subjects With Active Crohn's Disease
Celgene
NCT02367183
Triple Combination Therapy in High Risk Crohn's Disease (CD)
Takeda
NCT02764762
A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
University of Washington
NCT05651542
A Phase 2a Safety and Efficacy Open-Label Study of PRA023 in Subjects With Moderately to Severely Active Crohn's Disease
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT05013905
SMART-IBD App Trial
Children's Hospital Medical Center, Cincinnati
NCT06023667
Transcutaneous VNS to Treat Pediatric IBD
Northwell Health
NCT03863704
Digital Behavioral Interventions in Inflammatory Bowel Disease
Montefiore Medical Center
NCT04861597
Oral Administration of MB-102 Versus Dual Sugar Testing for Gut Permeability
MediBeacon
NCT03962998
Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas
Vanderbilt University Medical Center
NCT00517296
Effect of Grapes in Inflammatory Bowel Disease
Case Western Reserve University
NCT05972694
Anti-Inflammatory Effects of Mango Polyphenolics in Inflammatory Bowel Disease
Texas A&M University
NCT02227602
Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis
Stacy A. Kahn
NCT02330653
Analysis of Biologic Signatures in Crohn's Patients Undergoing Surgery
Weill Medical College of Cornell University
NCT06146335
FMT in Pediatric Crohn's Disease
Children's Hospital Los Angeles
NCT03194529
Flagyl Microbiome in Crohn's Disease
University of Louisville
NCT04682522
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 9 |
| Phase 3 | 5 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Crohn Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Crohn Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Crohn Disease page
72 registered trials, 34 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 34 Crohn Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Massachusetts General Hospital sponsors the most Crohn Disease trials on record, review their full trial history before evaluating a specific study. See Massachusetts General Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Crohn Disease condition card totals 72 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.