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ClinicalTrials.gov 16 recruiting now official registry

Contraception clinical trials

Every US clinical trial registered for Contraception — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

73 US clinical trials · 16 currently recruiting

The research picture

Contraception has 73 registered US clinical trials, 16 of them open to new participants right now — about 22% of the total.

16
recruiting participants now
22%
of trials open to enrollment
16
in Phase 3–4 (later-stage)
6
top sponsor: University of Utah

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 4 1,404 participants

Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start

University of Utah

NCT05444582

RECRUITING Phase 4 700 participants

Oral Contraceptive Pill (OCP) Pharmacogenomics

Yale University

NCT06334315

RECRUITING NA 656 participants

Contraceptive Efficacy Study of Ovaprene

Daré Bioscience

NCT06127199

RECRUITING NA 650 participants

Patient-centered Information on Permanent Contraception

University of California, San Francis

NCT06296797

RECRUITING NA 600 participants

A 3-way Crossover Clinical Investigation to Assess the Performance of Two Different Sized Polyurethane Condoms Versus a Latex Condom in Healthy Monogamous Couples.

Reckitt Benckiser Healthcare (UK) Limited

NCT06557499

RECRUITING NA 573 participants

Prospective Multi-Center Trial for FemBloc Permanent Birth Control

Femasys

NCT05977751

RECRUITING NA 400 participants

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Emory University

NCT05910580

RECRUITING NA 400 participants

Implementation of a Patient-centered, Reproductive Planning Decision Support Tool (MyPath) Among Women With Substance Use Disorder in the Immediate Postpartum Period

University of Pittsburgh

NCT04939012

RECRUITING NA 250 participants

Patient-clinical Linkages to Improve Trust and Engagement in Postpartum Healthcare

Jackson State University

NCT06481631

RECRUITING NA 204 participants

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

University of California, San Diego

NCT06960317

RECRUITING NA 150 participants

Hormonal Contraception Access Through Pharmacist Prescribing Implementation

EMPOWERX

NCT06823037

RECRUITING NA 64 participants

Intervening on Women's Health for Rural Young Cancer Survivors

University of California, San Diego

NCT06664034

RECRUITING Early Phase 1 52 participants

Endometrial Biopsy in Progestin Contraceptive Users

Oregon Health and Science University

NCT05760144

RECRUITING 33 participants

Influences of Long-acting Reversible Contraceptives on Iron Status and Physiological Responses to Extreme Environments in Women

United States Army Research Institute of Environmental Medicine

NCT06909695

RECRUITING Phase 4 18 participants

Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement

Arkansas Children's Hospital Research Institute

NCT05875571

RECRUITING Phase 4 12 participants

Etonogestrel Implant as Emergency Contraception

University of Colorado, Denver

NCT05237141

ACTIVE NOT RECRUITING NA 3,825 participants

Tipping Point: Using Social Network Theory to Accelerate Scale and Impact

University of California, San Diego

NCT05777473

ACTIVE NOT RECRUITING 1,341 participants

Birth Control to Improve Birth Spacing

Brigham and Women's Hospital

NCT05240066

ACTIVE NOT RECRUITING 1,030 participants

Quick Start of Highly Effective Contraception

University of Utah

NCT02076217

ACTIVE NOT RECRUITING 1,026 participants

The Over The Counter Pill National Study

Oregon Health and Science University

NCT05988983

ACTIVE NOT RECRUITING Phase 3 1,020 participants

Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy

Sumitomo Pharma Switzerland

NCT04756037

ACTIVE NOT RECRUITING Phase 4 348 participants

RCT Evaluating Standardized Counseling on Early Discontinuation for Irregular Bleeding in Nexplanon Users

Planned Parenthood of the St. Louis Region and Southwest Missouri

NCT04558229

ACTIVE NOT RECRUITING 255 participants

Assessing Adolescent Use of Nexplanon Over Time

University of Utah

NCT04889079

ACTIVE NOT RECRUITING 160 participants

Impact of Progestin-only Contraception on Bleeding Patterns in Individuals Initiating GATT

University of California, San Diego

NCT06230770

ACTIVE NOT RECRUITING NA 45 participants

FemBloc® Permanent Contraception - Confirmation Feasibility Trial

Femasys

NCT04273594

ACTIVE NOT RECRUITING NA 30 participants

Adolescent Subcutaneous (SQ) Injection Video Validation

Tufts Medical Center

NCT04997499

ACTIVE NOT RECRUITING 22 participants

Family Planning Elevated: Initiative Evaluation

University of Utah

NCT03877757

ACTIVE NOT RECRUITING NA 14 participants

The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB

Duke University

NCT05818254

COMPLETED 2,664 participants

Contraceptive Choice Center

Washington University School of Medicine

NCT02633631

COMPLETED NA 2,086 participants

UCSF College Health Study on Contraceptive Training and Education at Community Colleges

University of California, San Francis

NCT03519685

COMPLETED Phase 3 1,700 participants

Study of Safety and Efficacy of an Oral Contraceptive

Warner Chilcott

NCT00477633

COMPLETED NA 1,260 participants

Personal Responsibility Education Program Innovative Strategies: Digital Initiative for Youth

University of California, San Francis

NCT03765255

COMPLETED NA 1,076 participants

Effectiveness of Prolonged Use of IUD/Implant for Contraception

Indiana University

NCT02267616

COMPLETED NA 1,072 participants

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Johns Hopkins Bloomberg School of Public Health

NCT02904629

COMPLETED Phase 3 1,034 participants

A Multicenter, Non-Comparative Trial on the Contraceptive Efficacy, Safety, and Tolerability of LPRI-424, 13 Cycles

Insud Pharma

NCT03945513

COMPLETED Phase 4 937 participants

Study of Immediate Start of Progestin Contraceptives in Medical Abortion

Gynuity Health Projects

NCT01902485

COMPLETED 900 participants

Pharmacogenomics of Contraception: Genetic Variants and Etonogestrel Pharmacokinetics

University of Colorado, Denver

NCT03092037

COMPLETED NA 630 participants

Online Peer Influence on IUD Behaviors and Attitudes

University of California, San Francis

NCT02279043

COMPLETED 579 participants

Safety, Tolerability, and Efficacy of ellaOne® (Ulipristal Acetate) for Emergency Contraception in Postmenarcheal Adolescent Girls and Women

HRA Pharma

NCT01107106

COMPLETED NA 465 participants

Patient-Centered Reproductive Decision Support Tool for Women Veterans

VA Office of Research and Development

NCT04584294

COMPLETED 326 participants

Quantification of Immune Cells in Women Using Contraception (CHIC II)

University of Pittsburgh

NCT01873170

COMPLETED Phase 3 320 participants

A Multicenter Study to Evaluate the Safety of Seasonique, an Oral Contraceptive.

Duramed Research

NCT00196352

COMPLETED NA 240 participants

FemBloc® Permanent Contraception - Early Pivotal Trial

Femasys

NCT03433911

COMPLETED NA 214 participants

Assessing Satisfaction With Contraceptive Counseling Using Telephone Versus Video Telehealth Visits

Washington University School of Medicine

NCT05317468

COMPLETED 200 participants

Contraception Perspectives in Adolescents in Haiti

Children's Mercy Hospital Kansas City

NCT05252052

COMPLETED NA 200 participants

A Comparison of Short Interval vs. Routine Postpartum Visit on Contraceptive Initiation

Washington University School of Medicine

NCT02769676

COMPLETED Phase 1 140 participants

NES Gel-1, To Evaluate Nestorone Gel in Combination With Testosterone Gel

University of Washington

NCT00229593

COMPLETED NA 132 participants

Study of Self or Clinic Administration of DepoProvera

Carolyn L. Westhoff

NCT01019369

COMPLETED 123 participants

Comparison of the Levonorgestrel IUD and the Copper IUD Placed in the Immediate Postplacental Period: A Prospective Cohort Study

University of Colorado, Denver

NCT02067663

COMPLETED NA 119 participants

Improving Reproductive Health for Women in Opioid Medication-Assisted Treatment (OMAT)

Denver Health and Hospital Authority

NCT02794597

COMPLETED Phase 4 119 participants

A Study to Assess the Safety of a New Inserter Device for Paragard® (Intrauterine Copper Contraceptive)

CooperSurgical

NCT05309694

COMPLETED NA 116 participants

IUD Self-Removal: Evaluating an Online Guide for Self-removal in Clinical and Non-clinical Settings

University of Washington

NCT06042556

COMPLETED Phase 4 96 participants

Postpartum Etonogestrel Implant for Adolescents

University of North Carolina, Chapel Hill

NCT01666912

COMPLETED NA 84 participants

Video Counseling for Effective Postpartum Contraception

University of North Carolina, Chapel Hill

NCT02438800

COMPLETED NA 72 participants

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization

University of New Mexi

NCT02312739

COMPLETED Phase 1 60 participants

A Study to Evaluate the Pharmacokinetics (PK) of Medroxyprogesterone Acetate Following an Injection of TV-46046 in Healthy Women of Reproductive Age

Teva Branded Pharmaceutical Products R&D

NCT04682353

COMPLETED Phase 4 59 participants

Impact of Hormonal Contraception on HIV Acquisition and Transmission Risk

Lisa Haddad

NCT02357368

COMPLETED Phase 2 52 participants

Effect of Norgestrel 75 mcg on Cervical Mucus and Ovarian Activity During Perfect Use, After One Delayed Intake and After a Missed Pill

HRA Pharma

NCT03585712

COMPLETED 52 participants

Contraception for Solid Organ Transplant Patients: Utilizing Social Media

University of California, San Diego

NCT03979950

COMPLETED NA 49 participants

Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception

Femasys

NCT03067272

COMPLETED NA 40 participants

Home or Office Visit for the Insertion of Implantable Birth Control

Case Western Reserve University

NCT01816932

COMPLETED NA 37 participants

Reducing Adolescent Pregnancy in the Emergency Department

Children's Mercy Hospital Kansas City

NCT04744155

COMPLETED Phase 4 36 participants

Impact of Combined Hormonal Contraceptives on UPA

Oregon Health and Science University

NCT02577601

COMPLETED NA 30 participants

High-risk Obstetrical Patient Intervention Utilizing the Contraceptive CHOICE Project Script

University of California, San Diego

NCT03049592

COMPLETED Early Phase 1 25 participants

Inpatient Adolescent Contraception

Children's Mercy Hospital Kansas City

NCT04423068

COMPLETED 18 participants

Pharmacokinetics of Implanon in Obese Women

University of Chicago

NCT00724438

COMPLETED Phase 1 17 participants

Pharmacokinetic and Pharmacodynamic Study of Cyclofem

Sun Pharmaceutical Industries Limited

NCT01699022

COMPLETED NA 17 participants

Group Versus Individual Contraceptive Counseling for Resettled African Refugee Women

University of Utah

NCT02796586

COMPLETED Phase 1 16 participants

ORAL T-6: Oral Androgens in Man-6

University of Washington

NCT00663793

COMPLETED 13 participants

Changes in Vaginal, Cervical and Uterine Microflora With Levonorgestrel Intrauterine Device Placement

University of Utah

NCT01496898

COMPLETED Phase 1 12 participants

Study to Evaluate Suppression of Ovulation and Pharmacokinetics of Medroxyprogesterone Acetate Following Administration of TV-46046 in Women With Ovulatory Cycle

Teva Branded Pharmaceutical Products R&D

NCT02817464

COMPLETED Phase 4 8 participants

Glycosphingolipid Inhibition and Spermatogenesis in Man: A Pilot Study (MIG 2)

University of Washington

NCT00194649

COMPLETED Phase 4 7 participants

Intrauterine Contraceptive Device (IUD) Placement at Time of C-Section

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

NCT00733278

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 1
Phase 3 4
Phase 4 12

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Contraception Trial Landscape

ClinicalTrials.gov lists 73 US studies indexed under Contraception, and 16 of those are currently open to recruitment — roughly 22% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Contraception shows 16 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Contraception is led by University of Utah with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 73 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Contraception?

PlainTrial tracks 73 US clinical trials for Contraception, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Contraception?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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