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NCT05760144 · ClinicalTrials.gov registry record · Early Phase 1
Endometrial Biopsy in Progestin Contraceptive Users
A Early Phase 1 study of Contraception, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 52
- Enrollment target
- 1
- Study location
NCT05760144 is a Early Phase 1 study of Contraception that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 52 participants, below the 454-participant average among 72 other Contraception trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05760144, a Early Phase 1 study of Contraception, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 52 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to learn more about menstrual changes in progestin contraception users. The investigators are hoping to find out what changes in the endometrium lead to different bleeding patterns during the first year of progestin contraception use. Participants will choose to receive the contraceptive implant (Etonogestrel implant also called Nexplanon) or the contraceptive injectable (Depo-medroxyprogesterone acetate (DMPA) also called Depo-Provera) for up to 12 months. They will be asked to have 4 endometrial biopsies over the course of the study, as well as blood draws, physical exams, and pregnancy tests. Participants will also use a daily text message or email diary to report bleeding patterns. This study's plan is to comprehensively phenotype bleeding patterns and profile the entire endometrium using single-cell RNA seq data (sCRNAseq).
Conditions Studied
Interventions
- DRUG DMPA
- DRUG Etonogestrel implant
Study Locations (1)
Oregon
- OHSU - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2023-07-01 |
| Est. Completion | 2026-11 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05760144
The ClinicalTrials.gov registry entry for NCT05760144 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 454-participant average among 72 other Contraception trials with a reported enrollment target (89% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Contraception appearing as the primary indexed condition, and to 2 interventions - of which DMPA is the first listed.
NCT05760144 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.
Frequently Asked Questions
What is clinical trial NCT05760144 about?
NCT05760144 is a clinical study titled "Endometrial Biopsy in Progestin Contraceptive Users". The purpose of the study is to learn more about menstrual changes in progestin contraception users. The investigators are hoping to find out what changes in the endometrium lead to different bleeding patterns during the first year of progestin contraception use. Participants will choose to receive t...
What is the current status of trial NCT05760144?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 52 participants. The study started on 2023-07-01. Estimated completion is 2026-11.
What conditions does trial NCT05760144 study?
This clinical trial studies the following conditions: Contraception.
What interventions are being tested in trial NCT05760144?
The interventions under investigation include: DMPA (DRUG), Etonogestrel implant (DRUG).
Who is sponsoring clinical trial NCT05760144?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05760144 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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