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ClinicalTrials.gov 8 recruiting now official registry

Chronic Stroke clinical trials

Every US clinical trial registered for Chronic Stroke — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

21 US clinical trials · 8 currently recruiting

The research picture

Chronic Stroke has 21 registered US clinical trials, 8 of them open to new participants right now — about 38% of the total.

8
recruiting participants now
38%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: University of Illinois at Chicago

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 80 participants

Personalized Transcranial Direct Current Stimulation in Stroke Recovery

The Methodist Hospital Research Institute

NCT06286800

RECRUITING NA 60 participants

Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits

VA Office of Research and Development

NCT05296408

RECRUITING NA 42 participants

Wireless Nerve Stimulation Device To Enhance Recovery After Stroke

Baylor Research Institute

NCT04534556

RECRUITING NA 40 participants

Paired Vagus Nerve Stimulation Mechanisms

NYU Langone Health

NCT06716112

RECRUITING NA 30 participants

Home-based FES Training in People With Chronic Stroke

University of Illinois at Chicago

NCT05849532

RECRUITING NA 20 participants

Effect of NMES on Balance and Fall Risk in Chronic Stroke

University of Illinois at Chicago

NCT04957355

RECRUITING Phase 1 20 participants

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

NCT07053917

RECRUITING NA 6 participants

Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke

University of Washington

NCT05591196

ACTIVE NOT RECRUITING NA 234 participants

Outcomes and Health Economics of Stroke Using Rhythmic Auditory Stimulation

MedRhythms

NCT06051539

ACTIVE NOT RECRUITING NA 60 participants

Reflex Excitability in Post-stroke Stiff-Knee Gait

MetroHealth Medical Center

NCT04947865

ACTIVE NOT RECRUITING NA 25 participants

Hand Rehabilitation Study for Stroke Patients

University of California, San Francis

NCT03148106

ACTIVE NOT RECRUITING NA 20 participants

Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)

Medical University of South Carolina

NCT04655963

ACTIVE NOT RECRUITING NA 9 participants

intenSive UpPer Extremity Recovery Program for Chronic Stroke (SUPER)

The University of Texas Health Science Center, Houston

NCT05689502

COMPLETED NA 65 participants

Alternative Therapies for Improving Motor Impairment, Fall-risk and Overall Physical Function

University of Illinois at Chicago

NCT03758846

COMPLETED NA 46 participants

Can Patients With Chronic Stroke Regain Living Independence by Daily Energizing With Biophoton Generators

First Institute of All Medicines

NCT06049849

COMPLETED NA 44 participants

Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery

University of Cincinnati

NCT04553198

COMPLETED NA 31 participants

Facilitators and Barriers to the Clinical Implementation of MR-001

MedRhythms

NCT06003790

COMPLETED 16 participants

Assessing Leg Control in People With Chronic Stroke

University of Minnesota

NCT03271463

COMPLETED NA 12 participants

Post-stroke Fatigue, Inflammation, tDCS

Medical University of South Carolina

NCT05330988

COMPLETED NA 5 participants

Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke

University of Missouri-Columbia

NCT03602443

COMPLETED Early Phase 1 5 participants

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

Abington Memorial Hospital

NCT03352232

Phase Distribution

PhaseTrial count
Phase 1 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Stroke Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Chronic Stroke, and 8 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chronic Stroke shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chronic Stroke is led by University of Illinois at Chicago with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Stroke?

PlainTrial tracks 21 US clinical trials for Chronic Stroke, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Stroke?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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