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NCT06716112 · ClinicalTrials.gov registry record · NA
Paired Vagus Nerve Stimulation Mechanisms
A NA study of Chronic Stroke, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT06716112 is a NA study of Chronic Stroke that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 40 participants, roughly in line with the 42-participant average among 20 other Chronic Stroke trials with a reported enrollment target. The trial reports 2 study locations across 2 states.
The verdict
NCT06716112, a NA study of Chronic Stroke, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
In this mechanistic study, 40 individuals with chronic stroke will be implanted with a small vagus nerve stimulation (VNS) device. The study will use a randomized, blinded, crossover design to deliver two conditions in six-week blocks: active VNS or sham VNS, each paired with upper extremity (UE) motor rehabilitation. Assessment visits will occur before and after each block, and will examine neural pathway strength, functional connectivity, and motor and non-motor behaviors. Investigators will test for VNS-induced changes in motor, cognitive, and affective systems, and will identify biomarkers predictive of clinical response.
Conditions Studied
Interventions
- DEVICE Vagus Nerve Stimulation (VNS) Device
- DEVICE Sham VNS Device
- BEHAVIORAL Upper Extremity Rehabilitation
Study Locations (2)
New York
- NYU Langone Health - New York
Texas
- The University of Texas at Dallas - Richardson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-07-15 |
| Est. Completion | 2029-09 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06716112
The ClinicalTrials.gov registry entry for NCT06716112 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 42-participant average among 20 other Chronic Stroke trials with a reported enrollment target. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Stroke appearing as the primary indexed condition, and to 3 interventions - of which Vagus Nerve Stimulation (VNS) Device is the first listed.
NCT06716112 reports 2 study locations spanning 2 distinct geographic areas - top geographies include New York, Texas.
Frequently Asked Questions
What is clinical trial NCT06716112 about?
NCT06716112 is a clinical study titled "Paired Vagus Nerve Stimulation Mechanisms". In this mechanistic study, 40 individuals with chronic stroke will be implanted with a small vagus nerve stimulation (VNS) device. The study will use a randomized, blinded, crossover design to deliver two conditions in six-week blocks: active VNS or sham VNS, each paired with upper extremity (UE) mo...
What is the current status of trial NCT06716112?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-07-15. Estimated completion is 2029-09.
What conditions does trial NCT06716112 study?
This clinical trial studies the following conditions: Chronic Stroke.
What interventions are being tested in trial NCT06716112?
The interventions under investigation include: Vagus Nerve Stimulation (VNS) Device (DEVICE), Sham VNS Device (DEVICE), Upper Extremity Rehabilitation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06716112?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06716112 being conducted?
This trial has 2 study locations across New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
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