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Chronic Rhinosinusitis With Nasal Polyps: full-pipeline trial registry
7 of 12 indexed Chronic Rhinosinusitis With Nasal Polyps trials are currently recruiting.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 7 currently recruiting · #1,429 of 28,707 conditions by registered trial count
Chronic Rhinosinusitis With Nasal Polyps: 12 US clinical trials tracked, 7 recruiting.
Chronic Rhinosinusitis With Nasal Polyps is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Sanofi, running 4 of these trials.
Enrollment posture brief
Registry condition chronic-rhinosinusitis-with-nasal-polyps
OPEN 7 | RECR 58% | LATE 5 | EARLY 4 | RANK #1429 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Anterior Cruciate Ligament Reconstruction (58% recruiting · 12 trials)
Chronic Rhinosinusitis With Nasal Polyps lists 7 open slots (58% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chronic Rhinosinusitis With Nasal Polyps on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chronic Rhinosinusitis With Nasal Polyps is recruiting above its size-band peers.
7 of 12 indexed trials (58.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Chronic Rhinosinusitis With Nasal Polyps research.
Sanofi accounts for 4 of 12 trials (33.3%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Chronic Rhinosinusitis With Nasal Polyps enrolment sits around 79 participants.
Median target enrolment is 79 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.
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Chronic Rhinosinusitis With Nasal Polyps research is mostly interventional.
10 interventional and 2 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Sanofi
NCT06834347
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Sanofi
NCT06834360
3D Printing to Improve Nasal Irrigation Outcome
Ohio State University
NCT06118554
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
AstraZeneca
NCT06706817
Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study
Sanofi
NCT06914908
Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis
Montefiore Medical Center
NCT05246267
The Role of IL5 in Epithelial Cell Integrity
Johns Hopkins University
NCT05895929
A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps
Sanofi
NCT06454240
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis
AstraZeneca
NCT04851964
Mechanisms of Smell Improvement With Dupilumab.
Medical University of South Carolina
NCT05964465
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps
Amgen
NCT02170337
Tissue Immune Interaction in Nasal Polyposis
University of California, San Francisco
NCT04628442
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 3 | 4 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Chronic Rhinosinusitis With Nasal Polyps records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chronic Rhinosinusitis With Nasal Polyps trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chronic Rhinosinusitis With Nasal Polyps page
12 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Chronic Rhinosinusitis With Nasal Polyps trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Sanofi sponsors the most Chronic Rhinosinusitis With Nasal Polyps trials on record, review their full trial history before evaluating a specific study. See Sanofi's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Rhinosinusitis With Nasal Polyps condition card totals 12 registered trials; most-linked intervention Mometasone furoate nasal spray (MFNS); top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.