Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04628442 · ClinicalTrials.gov registry record
Tissue Immune Interaction in Nasal Polyposis
A clinical trial of Asthma and Chronic Rhinosinusitis With Nasal Polyps, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 38
- Enrollment target
- 1
- Study location
NCT04628442: Completed study of Asthma and Chronic Rhinosinusitis With Nasal Polyps, sponsored by University of California, San Francisco.
NCT04628442 is a study of Asthma and Chronic Rhinosinusitis With Nasal Polyps that has completed, run by University of California, San Francisco. The registered enrollment target is 38 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04628442, a study of Asthma and Chronic Rhinosinusitis With Nasal Polyps, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. Participants will be asked to donate leftover sino-nasal secretions, sino-nasal tissue and blood as well as undergo partial characterization. As optional extensions of the main study, participants may also undergo a biopsy of extra sino-nasal tissue for additional tissue analysis and/or a more detailed characterization visit performed in the UCSF Airway Center Research Center (ACRC).
Primary Outcome
This study enrolls chronic rhinosinusitis patients with and without nasal polyps. Investigators aim to compare the percentage of ILC2 and tuft cells present in nasal tissue and secretions between those who present with nasal polyps and without nasal polyps.
Conditions Studied
Interventions
- PROCEDURE Biopsy
- PROCEDURE Sinonasal Debridement Procedure
- PROCEDURE Nasal Polyp Removal
Study Locations (1)
California
- UCSF Airway Clinical Research Center - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2020-11-10 |
| Est. Completion | 2023-03-24 |
What the finished NCT04628442 record still lists
NCT04628442 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Asthma appearing as the primary indexed condition, and to 3 interventions - of which Biopsy is the first listed.
NCT04628442 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04628442 about?
NCT04628442 is a clinical study titled "Tissue Immune Interaction in Nasal Polyposis". This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. Participants will be asked to donate leftover sino-nasal secretions, sino-nasal tissue and blood as well as undergo partial characterization. As optional ex...
What is the current status of trial NCT04628442?
This trial is currently completed. The enrollment target is 38 participants. The study started on 2020-11-10. Estimated completion is 2023-03-24.
What conditions does trial NCT04628442 study?
This clinical trial studies the following conditions: Asthma, Chronic Rhinosinusitis With Nasal Polyps, Chronic Rhinosinusitis (Diagnosis).
What interventions are being tested in trial NCT04628442?
The interventions under investigation include: Biopsy (PROCEDURE), Sinonasal Debridement Procedure (PROCEDURE), Nasal Polyp Removal (PROCEDURE).
Who is sponsoring clinical trial NCT04628442?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04628442 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04628442's enrollment target sits among peer trials
38 285th of 374 higher than 89 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Innate Immunity in Allergic Asthma
RECRUITING
-
Automated Inhaler Monitoring for Asthma Medication Usage
RECRUITING · NA
-
Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
RECRUITING
-
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
RECRUITING · Phase 3
-
Escitalopram in Asthma Patients With Frequent Exacerbation
RECRUITING · Phase 2
-
Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma
RECRUITING · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01684904 · 38 participants · NA
Proton Therapy for Esophageal Cancer
- NCT03310879 · 38 participants · Phase 2
Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6
- NCT03896269 · 38 participants · Phase 1
CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
- NCT04085315 · 38 participants · Phase 1
Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI