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NCT02170337 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps
A Phase 1 study of Chronic Rhinosinusitis With Nasal Polyps, sponsored by Amgen.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
- 4
- Study locations
NCT02170337: Completed Phase 1 study of Chronic Rhinosinusitis With Nasal Polyps, sponsored by Amgen.
NCT02170337 is a Phase 1 study of Chronic Rhinosinusitis With Nasal Polyps that has completed, run by Amgen. The registered enrollment target is 41 participants, below the 139-participant average among 11 other Chronic Rhinosinusitis With Nasal Polyps trials with a reported enrollment target (71% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02170337, a Phase 1 study of Chronic Rhinosinusitis With Nasal Polyps, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
- 4
- Study locations
Study Summary
A randomized, double-blind, ascending multiple dose study in healthy volunteers and subjects with chronic rhinosinusitis with nasal polyps
Primary Outcome
Subject incidence of treatment-emergent adverse events, vital signs, physical examinations, laboratory safety tests, and 12-lead electrocardiograms (ECGs)
Conditions Studied
Interventions
- DRUG Placebo
- DRUG AMG 282
Study Locations (4)
California
- Research Site - Santa Monica
Colorado
- Research Site - Aurora
Florida
- Research Site - South Miami
Texas
- Research Site - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2014-07 |
| Est. Completion | 2016-05 |
| Phase | Phase 1 |
What the finished NCT02170337 record still lists
NCT02170337 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 139-participant average among 11 other Chronic Rhinosinusitis With Nasal Polyps trials with a reported enrollment target (71% lower).
The record links to 1 condition, with Chronic Rhinosinusitis With Nasal Polyps appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02170337 reports a single indexed study location in California, Colorado, Florida.
Frequently Asked Questions
What is clinical trial NCT02170337 about?
NCT02170337 is a clinical study titled "A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps". A randomized, double-blind, ascending multiple dose study in healthy volunteers and subjects with chronic rhinosinusitis with nasal polyps
What is the current status of trial NCT02170337?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2014-07. Estimated completion is 2016-05.
What conditions does trial NCT02170337 study?
This clinical trial studies the following conditions: Chronic Rhinosinusitis With Nasal Polyps.
What interventions are being tested in trial NCT02170337?
The interventions under investigation include: Placebo (DRUG), AMG 282 (DRUG).
Who is sponsoring clinical trial NCT02170337?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02170337 being conducted?
This trial has 4 study locations across California, Colorado, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Rhinosinusitis With Nasal Polyps
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Where NCT02170337's enrollment target sits among peer trials
41 10th of 11 higher than 2 of 11 other Chronic Rhinosinusitis With Nasal Polyps trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Rhinosinusitis With Nasal Polyps trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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