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NCT07059091 · ClinicalTrials.gov registry record · Phase 2
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
A Phase 2 study of Chronic Obstructive Pulmonary Disease (COPD) and Allergies, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 334
- Enrollment target
- 20
- Study locations
NCT07059091: Recruiting Phase 2 study of Chronic Obstructive Pulmonary Disease (COPD) and Allergies, sponsored by Johns Hopkins University.
NCT07059091 is a Phase 2 study of Chronic Obstructive Pulmonary Disease (COPD) and Allergies that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 334 participants, below the 642-participant average among 36 other Chronic Obstructive Pulmonary Disease (COPD) trials with a reported enrollment target (48% lower). The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07059091, a Phase 2 study of Chronic Obstructive Pulmonary Disease (COPD) and Allergies, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 334 participants
- Enrollment target
- 20
- Study locations
Study Summary
This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Each participant will be in the study for about 16 months, including 1-3 months of screening, 12 months of receiving the study drug at a clinic, and a follow-up call one month after your final clinic visit.
Primary Outcome
To determine the efficacy of omalizumab injection in reducing the annualized rate of moderate or severe exacerbations (primary outcome) over the course of 12 months among individuals with COPD having sensitization and exposure to any of a panel of common indoor aeroallergens.
Conditions Studied
Interventions
- DRUG Omalizumab (Xolair®)
- DRUG Sodium Chloride (NaCl) 0.9 %
Study Locations (20)
Illinois
- University of Illinois at Chicago - Chicago
- Northwestern University - Chicago
- Rush University Medical Center - Chicago
New York
- Mount Sinai, Icahn School of Medicine - New York
- Columbia University - New York
- Cornell University - New York
Michigan
- University of Michigan - Ann Arbor
- Henry Ford Health - Detroit
Pennsylvania
- Temple University - Philadelphia
- University of Pittsburgh - Pittsburgh
Alabama
- University of Alabama - Birmingham
Arizona
- University of Arizona- Tuscon - Tucson
California
- University of San Francisco - San Francisco
Colorado
- National Jewish Health - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 334 participants |
| Start Date | 2026-02-12 |
| Est. Completion | 2031-05 |
| Phase | Phase 2 |
What NCT07059091 shows while recruiting
NCT07059091 is an interventional study that assigns participants to a tested intervention. The registered 334 participants enrollment target is mid-sized for trials with a published cap, below the 642-participant average among 36 other Chronic Obstructive Pulmonary Disease (COPD) trials with a reported enrollment target (48% lower).
The record links to 2 conditions, with Chronic Obstructive Pulmonary Disease (COPD) appearing as the primary indexed condition, and to 2 interventions - of which Omalizumab (Xolair®) is the first listed.
NCT07059091 names 20 study sites across 14 states, led by Illinois, New York, Michigan.
Frequently Asked Questions
What is clinical trial NCT07059091 about?
NCT07059091 is a clinical study titled "Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD". This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Each participant will be in the study for about 16 months, including 1-3 months of screening, 12 months of receiving the study drug at a clinic, and a fol...
What is the current status of trial NCT07059091?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 334 participants. The study started on 2026-02-12. Estimated completion is 2031-05.
What conditions does trial NCT07059091 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease (COPD), Allergies.
What interventions are being tested in trial NCT07059091?
The interventions under investigation include: Omalizumab (Xolair®) (DRUG), Sodium Chloride (NaCl) 0.9 % (DRUG).
Who is sponsoring clinical trial NCT07059091?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07059091 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Obstructive Pulmonary Disease (COPD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07059091's enrollment target sits among peer trials
334 18th of 36 higher than 19 of 36 other Chronic Obstructive Pulmonary Disease (COPD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease (COPD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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