Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cataract: later-stage trial registry
20 of 85 indexed Cataract trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #165 of 28,707 conditions by registered trial count.
85 US clinical trials · 20 currently recruiting · #165 of 28,707 conditions by registered trial count
Cataract: 85 US clinical trials tracked, 20 recruiting.
Cataract is the subject of 85 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 30 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Alcon Research, running 12 of these trials.
Enrollment posture brief
Registry condition cataract
OPEN 20 | RECR 24% | LATE 30 | EARLY 5 | RANK #165 | SPON 12
Volume-matched condition peers
Nearest open-share peer: Acute Lymphoblastic Leukemia (ALL) (24% recruiting · 17 trials)
Cataract lists 20 open slots (24% of 85 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cataract on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cataract is recruiting below its size-band peers.
20 of 85 indexed trials (23.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cataract trials is spread across many organizations.
Alcon Research accounts for 12 of 85 trials (14.1%). 52 distinct sponsors appear on at least one study for this condition label.
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Typical Cataract enrolment sits around 94 participants.
Median target enrolment is 94 among the 84 trials that report a genuine target (sentinel values excluded). 46 of those (54.8%) plan for fewer than 100 participants.
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Cataract research is mostly interventional.
62 interventional and 23 observational studies make up this index (72.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
85 total, page 2 of 2
Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation
East Coast Institute for Research
NCT05827133
Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery
Carl Zeiss Meditec
NCT04747834
Ocular Tissue Levels of 1.5% Levofloxacin Ophthalmic Solution Compared to an Active Comparator
Santen
NCT00630019
Cataract Surgery to Obtain Human Lens Material for the Study of Nuclear Cataracts
National Eye Institute (NEI)
NCT00001613
Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
Milton S. Hershey Medical Center
NCT04676451
Evaluation of the EpiGlare Tester for the Measurement of Glare-Induced Changes in BSCVA in Subjects With and Without Cataracts
Epico
NCT04739397
Conventional Surgery vs. Verion/VerifEye
Carolina Eyecare Physicians
NCT02513745
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
Iworks Laser and Vision Center
NCT05372315
Monofocal IOL Visual Outcomes When Targeting Mini Monovision
Carolina Eyecare Physicians
NCT05069415
Rotational Stability of the AcrySof® Toric
Alcon Research
NCT00762216
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
Alcon Research
NCT01045733
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
Alcon Research
NCT01166971
A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
Ocular Therapeutix
NCT04539548
Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery
Alcon Research
NCT00870103
Symfony vs Vivity in Dim Light
Carolina Eyecare Physicians
NCT06229106
Dropless vs. Standard Drops Contralateral Eye Study
Carolina Eyecare Physicians
NCT02515045
Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL
Johnson & Johnson Surgical Vision
NCT04210232
Clinical Comparison of Length of Cataract Procedures With Zeiss Lumera Versus Older Zeiss Microscope
Toyos Clinic
NCT03298841
Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.
Indiana University School of Medicine
NCT00355446
Penetrance of Third Generation Fluoroquinolones in Eyes With Functioning Filtering Blebs
Indiana University School of Medicine
NCT00392275
Intraocular Steroid After Cataract Surgery Study
Dean Health System
NCT00478764
Evaluation of Effective Lens Position With a Uniplanar Bi-aspheric IOL
Lenstec Incorporated
NCT01248572
Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert
Wolstan and Goldberg Eye Associates
NCT04465864
Veracity Surgical: A Time/Motion and Quality of Care Study
Research Insight
NCT04337892
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
Mann Eye Institute
NCT06550375
Prophylactic Treatment: Lessdrops™ vs Standard Drops Regimen
Carolina Eyecare Physicians
NCT03578276
Visual Function and Patient Satisfaction After Bilateral Implantation of AcrySof Natural ReSTOR (Model SN60D3) or AcrySof Natural Monofocal (Model SN60AT)
Alcon Research
NCT00759668
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
Newsom Eye & Laser Center
NCT05518539
The Evaluation of Balanced Salt Solution During Cataract Surgery
Adam Fedyk, MD, FACS
NCT05853978
Binocular Custom Vision Utilizing The Light Adjustable Lens (LAL)
Vance Thompson Vision
NCT04533191
Evaluation of the Aspheric ReSTOR IOL After Routine Cataract Extraction
Medical University of South Carolina
NCT00720005
Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study
Vance Thompson Vision
NCT07129980
Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
Massachusetts Eye and Ear Infirmary
NCT04057053
Test of QLS Device to Detect Early Cataracts
National Eye Institute (NEI)
NCT00001617
Ketorolac vs. Steroid in the Prevention of CME
Innovative Medical
NCT00348244
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 1 |
| Phase 3 | 10 |
| Phase 4 | 20 |
Top Sponsors
Named interventions
Most-linked intervention names on Cataract records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cataract trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cataract page
85 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 20 Cataract trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Alcon Research sponsors the most Cataract trials on record, review their full trial history before evaluating a specific study. See Alcon Research's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cataract condition card totals 85 registered trials; most-linked intervention Timolol Maleate Ophthalmic Solution, 0.5%; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.