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NCT04539548 · ClinicalTrials.gov registry record · Phase 3

A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract

A Phase 3 study of Cataract, sponsored by Ocular Therapeutix.

Completed
Registry status
Phase 3
Development phase
65
Enrollment target
14
Study locations

NCT04539548 is a Phase 3 study of Cataract that has completed, run by Ocular Therapeutix. The registered enrollment target is 65 participants, below the 228-participant average among 83 other Cataract trials with a reported enrollment target (71% lower). The trial reports 14 study locations across 12 states.

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The verdict

NCT04539548, a Phase 3 study of Cataract, has completed, sponsored by Ocular Therapeutix.

COMPLETED
Registry status
Phase 3
Development phase
65 participants
Enrollment target
14
Study locations

Study Summary

To assess the safety of Dextenza compared to an active control, prednisolone acetate suspension, for the treatment of postoperative pain and inflammation following ocular surgery for pediatric cataract.

Conditions Studied

Interventions

  • DRUG Dextenza Ophthalmic Insert
  • DRUG Prednisolone acetate ophthalmic suspension USP 1%

Study Locations (14)

Colorado

  • Ocular Therapeutix - Aurora
  • Ocular Therapeutix - Fort Collins

Minnesota

  • Ocular Therapeutix - Minneapolis
  • Ocular Therapeutix - Rochester

Florida

  • Ocular Therapeutix - Jacksonville

Indiana

  • Ocular Therapeutix - Indianapolis

Kentucky

  • Ocular Therapeutix - Lexington

Massachusetts

  • Ocular Therapeutix - Boston

Missouri

  • Ocular Therapeutix - St Louis

Pennsylvania

  • Ocular Therapeutix - Erie

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2020-09-04
Est. Completion 2023-12-21
Phase Phase 3

Sponsor

Ocular Therapeutix

20 total trials

What the Registry Record Tells You About NCT04539548

The ClinicalTrials.gov registry entry for NCT04539548 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 65 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 228-participant average among 83 other Cataract trials with a reported enrollment target (71% lower). The listed sponsor is Ocular Therapeutix, which has 20 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cataract appearing as the primary indexed condition, and to 2 interventions - of which Dextenza Ophthalmic Insert is the first listed.

NCT04539548 reports 14 study locations spanning 12 distinct geographic areas - top geographies include Colorado, Minnesota, Florida.

Frequently Asked Questions

What is clinical trial NCT04539548 about?

NCT04539548 is a clinical study titled "A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract". To assess the safety of Dextenza compared to an active control, prednisolone acetate suspension, for the treatment of postoperative pain and inflammation following ocular surgery for pediatric cataract.

What is the current status of trial NCT04539548?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 65 participants. The study started on 2020-09-04. Estimated completion is 2023-12-21.

What conditions does trial NCT04539548 study?

This clinical trial studies the following conditions: Cataract.

What interventions are being tested in trial NCT04539548?

The interventions under investigation include: Dextenza Ophthalmic Insert (DRUG), Prednisolone acetate ophthalmic suspension USP 1% (DRUG).

Who is sponsoring clinical trial NCT04539548?

This trial is sponsored by Ocular Therapeutix, which has 20 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04539548 being conducted?

This trial has 14 study locations across Colorado, Florida, Indiana, Kentucky, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.