Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00355446 · ClinicalTrials.gov registry record · Phase 4
Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.
A Phase 4 study of Cataract, sponsored by Indiana University School of Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 48
- Enrollment target
- 4
- Study locations
NCT00355446: Completed Phase 4 study of Cataract, sponsored by Indiana University School of Medicine.
NCT00355446 is a Phase 4 study of Cataract that has completed, run by Indiana University School of Medicine. The registered enrollment target is 48 participants, below the 228-participant average among 83 other Cataract trials with a reported enrollment target (79% lower). The trial reports 4 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00355446, a Phase 4 study of Cataract, has completed, sponsored by Indiana University School of Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 48 participants
- Enrollment target
- 4
- Study locations
Study Summary
The purpose of this study is to assay human aqueous for bimatoprost and the presence of any metabolites, especially prostaglandin analogs. Hypothesis:Bimatoprost is not metabolized to a prostaglandin F-2-alpha analog in human eyes * Bimatoprost levels in human aqueous peak approximately three hours post dosing
Conditions Studied
Interventions
- DRUG Bimatoprost 0.03%
Study Locations (4)
Indiana
- University Hospital - Indianapolis
- Veterans Affairs Medical Center - Indianapolis
- Wishard Memorial Hospital - Indianapolis
- IU Eye at Carmel - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2001-07 |
| Est. Completion | 2004-10 |
| Phase | Phase 4 |
What the finished NCT00355446 record still lists
NCT00355446 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 228-participant average among 83 other Cataract trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Cataract appearing as the primary indexed condition, and to 1 intervention - of which Bimatoprost 0.03% is the first listed.
NCT00355446 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT00355446 about?
NCT00355446 is a clinical study titled "Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.". The purpose of this study is to assay human aqueous for bimatoprost and the presence of any metabolites, especially prostaglandin analogs. Hypothesis:Bimatoprost is not metabolized to a prostaglandin F-2-alpha analog in human eyes * Bimatoprost levels in human aqueous peak approximately three hours...
What is the current status of trial NCT00355446?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 48 participants. The study started on 2001-07. Estimated completion is 2004-10.
What conditions does trial NCT00355446 study?
This clinical trial studies the following conditions: Cataract.
What interventions are being tested in trial NCT00355446?
The interventions under investigation include: Bimatoprost 0.03% (DRUG).
Who is sponsoring clinical trial NCT00355446?
This trial is sponsored by Indiana University School of Medicine, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00355446 being conducted?
This trial has 4 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cataract
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00355446's enrollment target sits among peer trials
48 60th of 83 higher than 23 of 83 other Cataract trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cataract trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
RECRUITING · Phase 4
-
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
RECRUITING · Phase 4
-
Evaluation of a Monofocal Intraocular Lens
RECRUITING · Phase 4
-
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
RECRUITING · Phase 4
-
Odyssey Evaluation in Post LASIK Patients
RECRUITING · Phase 4
-
Dropless vs. Standard Drops Contralateral Eye Study
COMPLETED · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01765777 · 48 participants · NA
Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain
- NCT03073343 · 48 participants · NA
A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine
- NCT03431064 · 48 participants
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
- NCT03514602 · 48 participants · NA
Maternal Smoking Cessation and Pediatric Obesity Prevention
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia