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NCT06624475 · ClinicalTrials.gov registry record · Phase 2
Neoadjuvant Nivolumab + Relatlimab (Opdualag) Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma
A Phase 2 study of Basal Cell Carcinoma, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 3
- Study locations
NCT06624475: Recruiting Phase 2 study of Basal Cell Carcinoma, sponsored by University of California, San Diego.
NCT06624475 is a Phase 2 study of Basal Cell Carcinoma that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 30 participants, below the 103-participant average among 24 other Basal Cell Carcinoma trials with a reported enrollment target (71% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06624475, a Phase 2 study of Basal Cell Carcinoma, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a Phase 2 clinical trial with a 2:1 randomization comparing neoadjuvant Nivolumab + Relatlimab (Opdualag) vs neoadjuvant Nivolumab in patients with resectable high risk basal cell carcinoma (HR BCC)
Primary Outcome
The primary endpoint of this study is to evaluate the pathologic response rate (pathological complete response \[pCR\] plus major pathological response \[MPR\])) and the clinical complete response rate of Opdualag and Nivolumab in patients with resectable High-Risk Basal Cell Carcinoma.
Conditions Studied
Interventions
- DRUG Nivolumab
- DRUG Relatlimab plus Nivolumab
Study Locations (3)
California
- University of California, Irvine - Irvine
- University of California, San Diego Moores Cancer Center - La Jolla
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-08-21 |
| Est. Completion | 2028-05 |
| Phase | Phase 2 |
What NCT06624475 shows while recruiting
NCT06624475 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 103-participant average among 24 other Basal Cell Carcinoma trials with a reported enrollment target (71% lower).
The record links to 1 condition, with Basal Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Nivolumab is the first listed.
NCT06624475 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06624475 about?
NCT06624475 is a clinical study titled "Neoadjuvant Nivolumab + Relatlimab (Opdualag) Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma". This is a Phase 2 clinical trial with a 2:1 randomization comparing neoadjuvant Nivolumab + Relatlimab (Opdualag) vs neoadjuvant Nivolumab in patients with resectable high risk basal cell carcinoma (HR BCC)
What is the current status of trial NCT06624475?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-08-21. Estimated completion is 2028-05.
What conditions does trial NCT06624475 study?
This clinical trial studies the following conditions: Basal Cell Carcinoma.
What interventions are being tested in trial NCT06624475?
The interventions under investigation include: Nivolumab (DRUG), Relatlimab plus Nivolumab (DRUG).
Who is sponsoring clinical trial NCT06624475?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06624475 being conducted?
This trial has 3 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Basal Cell Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06624475's enrollment target sits among peer trials
30 19th of 24 higher than 6 of 24 other Basal Cell Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Basal Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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