Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Autosomal Dominant Polycystic Kidney Disease clinical trials
4 of 10 indexed Autosomal Dominant Polycystic Kidney Disease trials are currently recruiting.
10 US clinical trials · 4 currently recruiting
Autosomal Dominant Polycystic Kidney Disease is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 5 of these trials.
The research picture
Autosomal Dominant Polycystic Kidney Disease has 10 registered US clinical trials, 4 of them open to new participants right now, about 40% of the total.
- 4
- recruiting participants now
- 40%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Mayo Clinic
Active & Recent Trials
10 total, page 1 of 1
A Study to Assess Adverse Events and Effectiveness of IntraVenous Infusions of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
AbbVie
NCT06902558
NOX4 and Related Biomarkers in ADPKD
Mayo Clinic
NCT04630613
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Mayo Clinic
NCT04344769
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
AstraZeneca
NCT07228364
Role of ROS and cAMP-PKA Biomarkers in ADPKD
Mayo Clinic
NCT07217158
A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD
Mayo Clinic
NCT05193981
Intrarenal Microvasculature in ADPKD
Mayo Clinic
NCT05288998
ADPKD Cohort Study
Emory University
NCT02084849
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease
University of Pittsburgh
NCT01039987
Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD
Otsuka Pharmaceutical Development & Commercialization
NCT01210560
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Autosomal Dominant Polycystic Kidney Disease Trial Landscape
10 indexed Autosomal Dominant Polycystic Kidney Disease studies · 4 recruiting (40%).
Phase mix: 0 late (III/IV) vs 3 early (I/II).
Top sponsor: Mayo Clinic (5 trials), 5 others listed. 10 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Autosomal Dominant Polycystic Kidney Disease?
PlainTrial tracks 10 US clinical trials for Autosomal Dominant Polycystic Kidney Disease, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Autosomal Dominant Polycystic Kidney Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.