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NCT05193981 · ClinicalTrials.gov registry record

A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD

A clinical trial of Autosomal Dominant Polycystic Kidney Disease, sponsored by Mayo Clinic.

Active
Registry status
80
Enrollment target
1
Study location

NCT05193981: Active study of Autosomal Dominant Polycystic Kidney Disease, sponsored by Mayo Clinic.

NCT05193981 is a study of Autosomal Dominant Polycystic Kidney Disease that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 80 participants, below the 153-participant average among 9 other Autosomal Dominant Polycystic Kidney Disease trials with a reported enrollment target (48% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05193981, a study of Autosomal Dominant Polycystic Kidney Disease, is active but no longer recruiting, sponsored by Mayo Clinic.

ACTIVE NOT RECRUITING
Registry status
80 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess homocysteine metabolism and systemic endothelial function at the early stages of the disease and determine the prognostic value of homocysteine, related metabolites, and markers of endothelial function and injury to estimate renal disease severity and progression in patients with early Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Primary Outcome

TKV determined by MRI

Conditions Studied

Autosomal Dominant Polycystic Kidney Disease

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-09-14
Est. Completion 2026-06
Mayo Clinic

2,844 total trials

What the registry record for NCT05193981 still lists

NCT05193981 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 153-participant average among 9 other Autosomal Dominant Polycystic Kidney Disease trials with a reported enrollment target (48% lower).

The record links to 1 condition, with Autosomal Dominant Polycystic Kidney Disease appearing as the primary indexed condition, and to 0 interventions.

NCT05193981 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT05193981 about?

NCT05193981 is a clinical study titled "A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD". The purpose of this study is to assess homocysteine metabolism and systemic endothelial function at the early stages of the disease and determine the prognostic value of homocysteine, related metabolites, and markers of endothelial function and injury to estimate renal disease severity and progressi...

What is the current status of trial NCT05193981?

This trial is currently active not recruiting. The enrollment target is 80 participants. The study started on 2021-09-14. Estimated completion is 2026-06.

What conditions does trial NCT05193981 study?

This clinical trial studies the following conditions: Autosomal Dominant Polycystic Kidney Disease.

Who is sponsoring clinical trial NCT05193981?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05193981 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Autosomal Dominant Polycystic Kidney Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05193981's enrollment target sits among peer trials

80 5th of 9 higher than 5 of 9 other Autosomal Dominant Polycystic Kidney Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Autosomal Dominant Polycystic Kidney Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT05193981, the US trial registry maintained by the National Library of Medicine. NCT05193981 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.