Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Bipolar II Disorder: early-phase trial registry
7 of 15 indexed Bipolar II Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,140 of 28,707 conditions by registered trial count.
15 US clinical trials · 7 currently recruiting · #1,140 of 28,707 conditions by registered trial count
Bipolar II Disorder: 15 US clinical trials tracked, 7 recruiting.
Bipolar II Disorder is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 2 of these trials.
Enrollment posture brief
Registry condition bipolar-ii-disorder
OPEN 7 | RECR 47% | LATE 4 | EARLY 7 | RANK #1140 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Autism (47% recruiting · 105 trials)
Bipolar II Disorder lists 7 open slots (47% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Bipolar II Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Bipolar II Disorder recruits in line with its size-band peers.
7 of 15 indexed trials (46.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Bipolar II Disorder trials is spread across many organizations.
University of Pittsburgh accounts for 2 of 15 trials (13.3%). 13 distinct sponsors appear on at least one study for this condition label.
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Most Bipolar II Disorder trials plan to enrol fewer than 100 people.
Median target enrolment is 40 among the 15 trials that report a genuine target (sentinel values excluded). 12 of those (80%) plan for fewer than 100 participants.
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Bipolar II Disorder research is mostly interventional.
14 interventional and 1 observational studies make up this index (93.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
15 total, page 1 of 1
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Xenon Pharmaceuticals
NCT07172516
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
AbbVie
NCT06696755
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
Mayo Clinic
NCT07213466
Children's Bipolar Network Treatment Trial I
University of California, Los Angeles
NCT05427123
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Medical University of South Carolina
NCT05064319
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
NCT06706232
Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
Andrew Krystal
NCT07127913
Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression
Mclean Hospital
NCT03484494
Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar Disorder
BioXcel Therapeutics
NCT07116694
Psilocybin Therapy for Depression in Bipolar II Disorder
University of California, San Francisco
NCT05065294
The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.
Mayo Clinic
NCT03156504
Sensoril(Ashwaganhda)for Bipolar Disorder
University of Pittsburgh
NCT00761761
Treating Smokers With Mental Illness
University of Minnesota
NCT03822416
Psychotherapy for Bipolar II Depression, Pilot Study, Phase II
University of Pittsburgh
NCT00411463
A Single Blind Study of Cranial Electrical Stimulation in Bipolar II Disorder
Beth Israel Medical Center
NCT01909011
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 7 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Bipolar II Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Bipolar II Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Bipolar II Disorder page
15 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Bipolar II Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Pittsburgh sponsors the most Bipolar II Disorder trials on record, review their full trial history before evaluating a specific study. See University of Pittsburgh's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Bipolar II Disorder condition card totals 15 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.