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Atrial Flutter clinical trials
Every US clinical trial registered for Atrial Flutter — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
25 US clinical trials · 4 currently recruiting
The research picture
Atrial Flutter has 25 registered US clinical trials, 4 of them open to new participants right now — about 16% of the total.
- 4
- recruiting participants now
- 16%
- of trials open to enrollment
- 8
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Sanofi
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Get With the Guidelines Atrial Fibrillation Registry
American Heart Association
NCT06245187
Pericardiotomy in Cardiac Surgery
Population Health Research Institute
NCT06486636
The Z Stitch Early Bed Rest Assessment Study
Oregon Health and Science University
NCT06087497
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Tulane University
NCT05014802
RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.
Cortex
NCT05883631
Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation
Bristol-Myers Squibb
NCT00412984
A Trial With Dronedarone to Prevent Hospitalization or Death in Patients With Atrial Fibrillation
Sanofi
NCT00174785
Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter
Sanofi
NCT00233441
American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm
Sanofi
NCT00259376
Atrial Fibrillation/Flutter Outcome Risk Determination
Vanderbilt University
NCT01138644
Effect of Oral and Intravenous Diltiazem Protocol for Emergency Department Atrial Fibrillation
Corewell Health South
NCT05391893
Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery
MaineHealth
NCT00953212
Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter
Boston Scientific Corporation
NCT01253200
Study to Determine the Response and Effectiveness of RSD1235 in Subjects With Atrial Fibrillation or Atrial Flutter
Astellas Pharma
NCT00115791
iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology
Columbia University
NCT02731326
Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies
Catheter Robotics
NCT01139814
Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism
Vanderbilt University Medical Center
NCT01976507
Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography
Elad Anter
NCT02213666
Impact of an Atrial Fibrillation Decision Support Tool (AFDST) on Thromboprophylaxis for Atrial Fibrillation
University of Cincinnati
NCT02524977
A Phase II/III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Flutter
Advanz Pharma
NCT00476112
FREEZE-AFIB Post-Market Study
AtriCure
NCT05089877
Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant
Abramson Cancer Center at Penn Medicine
NCT04118530
Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias
Apple
NCT03769207
ArcticLine Feasibility Study
Medtronic Cardiac Ablation Solutions
NCT03604263
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects
Solvay Pharmaceuticals
NCT00126022
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 6 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Atrial Flutter Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Atrial Flutter, and 4 of those are currently open to recruitment — roughly 16% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Atrial Flutter shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Atrial Flutter is led by Sanofi with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Atrial Flutter?
PlainTrial tracks 25 US clinical trials for Atrial Flutter, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Atrial Flutter?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.