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ClinicalTrials.gov 4 recruiting now later-stage tilt

Atrial Flutter: later-stage trial registry

4 of 25 indexed Atrial Flutter trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 4 currently recruiting · #652 of 28,707 conditions by registered trial count

Atrial Flutter: 25 US clinical trials tracked, 4 recruiting.

Atrial Flutter is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Sanofi, running 3 of these trials.

Enrollment posture brief

Registry condition atrial-flutter

OPEN 4 | RECR 16% | LATE 8 | EARLY 2 | RANK #652 | SPON 3

Nearest open-share peer: Avascular Necrosis (16% recruiting · 25 trials)

Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%Atrial Flutter (this)16%
Open-enrollment share among volume-matched conditions near Atrial Flutter

Atrial Flutter lists 4 open slots (16% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Atrial Flutter on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Atrial Flutter is recruiting below its size-band peers.

    4 of 25 indexed trials (16%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Atrial Flutter trials is spread across many organizations.

    Sanofi accounts for 3 of 25 trials (12%). 23 distinct sponsors appear on at least one study for this condition label.

  3. Typical Atrial Flutter enrolment sits around 276 participants.

    Median target enrolment is 276 among the 24 trials that report a genuine target (sentinel values excluded). 8 of those (33.3%) plan for fewer than 100 participants.

  4. Atrial Flutter research is mostly interventional.

    19 interventional and 6 observational studies make up this index (76% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 36Phase 42

Open and recent trials

25 total, page 1 of 1

RECRUITING 17,198 participants

Get With the Guidelines Atrial Fibrillation Registry

American Heart Association

NCT06245187

RECRUITING NA 1,400 participants

Pericardiotomy in Cardiac Surgery

Population Health Research Institute

NCT06486636

RECRUITING NA 200 participants

The Z Stitch Early Bed Rest Assessment Study

Oregon Health and Science University

NCT06087497

RECRUITING 50 participants

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Tulane University

NCT05014802

ACTIVE NOT RECRUITING NA 400 participants

RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

Cortex

NCT05883631

COMPLETED Phase 3 20,976 participants

Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation

Bristol-Myers Squibb

NCT00412984

COMPLETED Phase 3 4,628 participants

A Trial With Dronedarone to Prevent Hospitalization or Death in Patients With Atrial Fibrillation

Sanofi

NCT00174785

COMPLETED Phase 2 673 participants

Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter

Sanofi

NCT00233441

COMPLETED Phase 3 629 participants

American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm

Sanofi

NCT00259376

COMPLETED 519 participants

Atrial Fibrillation/Flutter Outcome Risk Determination

Vanderbilt University

NCT01138644

COMPLETED Phase 4 444 participants

Effect of Oral and Intravenous Diltiazem Protocol for Emergency Department Atrial Fibrillation

Corewell Health South

NCT05391893

COMPLETED Phase 3 304 participants

Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery

MaineHealth

NCT00953212

COMPLETED NA 302 participants

Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter

Boston Scientific Corporation

NCT01253200

COMPLETED Phase 3 276 participants

Study to Determine the Response and Effectiveness of RSD1235 in Subjects With Atrial Fibrillation or Atrial Flutter

Astellas Pharma

NCT00115791

COMPLETED NA 264 participants

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

Columbia University

NCT02731326

COMPLETED NA 181 participants

Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies

Catheter Robotics

NCT01139814

COMPLETED Phase 4 101 participants

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

Vanderbilt University Medical Center

NCT01976507

COMPLETED 72 participants

Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography

Elad Anter

NCT02213666

COMPLETED NA 70 participants

Impact of an Atrial Fibrillation Decision Support Tool (AFDST) on Thromboprophylaxis for Atrial Fibrillation

University of Cincinnati

NCT02524977

COMPLETED Phase 2 60 participants

A Phase II/III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Flutter

Advanz Pharma

NCT00476112

COMPLETED 39 participants

FREEZE-AFIB Post-Market Study

AtriCure

NCT05089877

COMPLETED 21 participants

Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant

Abramson Cancer Center at Penn Medicine

NCT04118530

COMPLETED NA 17 participants

Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias

Apple

NCT03769207

COMPLETED NA 17 participants

ArcticLine Feasibility Study

Medtronic Cardiac Ablation Solutions

NCT03604263

COMPLETED Phase 3

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

Solvay Pharmaceuticals

NCT00126022

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 6
Phase 4 2

Top Sponsors

Named interventions

Most-linked intervention names on Atrial Flutter records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

placebo Drug
3 trials
Educational Intervention Only Behavioral
1 trials
Celivarone (ssr149744c) Drug
1 trials
Intracardiac Imaging Device
1 trials
ArcticLine Cardiac Cryoablation Catheter Device
1 trials
Vernakalant Injection 20 mg/mL Drug
1 trials
Intravenous drug Drug
1 trials
Oral Drug
1 trials

US sites by state

Facility locations filed on Atrial Flutter trials. A trial with sites in several states counts in each.

Michigan 7 trials
California 6 trials
New York 5 trials
New Jersey 5 trials
Virginia 4 trials
Tennessee 4 trials
Pennsylvania 4 trials
Ohio 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Atrial Flutter page

25 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Atrial Flutter trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Sanofi sponsors the most Atrial Flutter trials on record, review their full trial history before evaluating a specific study. See Sanofi's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atrial Flutter condition card totals 25 registered trials; most-linked intervention placebo; top US site state Michigan. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.