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Pericardiotomy in Cardiac Surgery
NCT06486636 · View on ClinicalTrials.gov ↗
Study Summary
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
Conditions Studied
Interventions
- PROCEDURE Left Posterior Pericardiotomy
Study Locations (4)
New York
- Weill Cornell Medicine — New York
Vienna
- Medical University Vienna — Vienna
Ontario
- Hamilton Health Sciences — Hamilton
Foggia
- University of Foggia, Policlinico Foggia — Foggia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,400 participants |
| Start Date | 2024-10-21 |
| Est. Completion | 2031-09-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06486636
The ClinicalTrials.gov registry entry for NCT06486636 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Population Health Research Institute, which has 68 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Atrial Fibrillation appearing as the primary indexed condition, and to 1 intervention — of which Left Posterior Pericardiotomy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06486636 reports 4 study locations spanning 4 distinct geographic areas — top geographies include New York, Vienna, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06486636 about?
NCT06486636 is a clinical study titled "Pericardiotomy in Cardiac Surgery". PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
What is the current status of trial NCT06486636?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,400 participants. The study started on 2024-10-21. Estimated completion is 2031-09-01.
What conditions does trial NCT06486636 study?
This clinical trial studies the following conditions: Atrial Fibrillation, Atrial Flutter, Cardiac Events. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06486636?
The interventions under investigation include: Left Posterior Pericardiotomy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06486636?
This trial is sponsored by Population Health Research Institute, which has 68 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06486636 being conducted?
This trial has 4 study locations across New York, Vienna, Ontario, Foggia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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