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ClinicalTrials.gov 2 recruiting now official registry

Cannabis Dependence clinical trials

2 of 13 indexed Cannabis Dependence trials are currently recruiting.

13 US clinical trials · 2 currently recruiting

Cannabis Dependence is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Drug Abuse (NIDA), running 2 of these trials.

The research picture

Cannabis Dependence has 13 registered US clinical trials, 2 of them open to new participants right now, about 15% of the total.

2
recruiting participants now
15%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: National Institute on Drug Abuse (NIDA)
Phase 12Phase 22Phase 42

Active & Recent Trials

13 total, page 1 of 1

RECRUITING 100 participants

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Yale University

NCT01730781

RECRUITING NA 80 participants

Neuroimaging of Adolescent Cannabis Use Treatment

Indiana University

NCT07340554

ACTIVE NOT RECRUITING NA 10 participants

Breathwork-assisted Treatment for Cannabis Use Disorder

Elias Dakwar

NCT05219825

COMPLETED 822 participants

Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

National Institute on Drug Abuse (NIDA)

NCT01603992

COMPLETED Phase 4 124 participants

Improving Substance Use and Clinical Outcomes in Heavy Cannabis Users With Quetiapine

Northwell Health

NCT01153490

COMPLETED 120 participants

Risk Perception in Drug-Dependent Adults With and Without Schizophrenia

National Institute on Drug Abuse (NIDA)

NCT01031563

COMPLETED Phase 2 70 participants

Treatment for Cannabis Withdrawal and Dependence

The Scripps Research Institute

NCT01611948

COMPLETED Phase 2 70 participants

Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal

Yale University

NCT01618656

COMPLETED Phase 1 68 participants

Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders

Louisiana State University and A&M College

NCT01875796

COMPLETED NA 35 participants

Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting

Hunter Holmes Mcguire Veteran Affairs Medical Center

NCT03662529

COMPLETED NA 33 participants

Targeting Tobacco Cessation During Treatment for Cannabis Use Disorders

Dartmouth-Hitchcock Medical Center

NCT01834794

COMPLETED Phase 1 24 participants

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents

Medical University of South Carolina

NCT00542750

COMPLETED Phase 4 11 participants

Reducing Cannabis Overuse With Prazosin

VA Puget Sound Health Care System

NCT04721353

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cannabis Dependence Trial Landscape

13 indexed Cannabis Dependence studies · 2 recruiting (15%).

Phase mix: 2 late (III/IV) vs 4 early (I/II).

Top sponsor: National Institute on Drug Abuse (NIDA) (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cannabis Dependence?

PlainTrial tracks 13 US clinical trials for Cannabis Dependence, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cannabis Dependence?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.