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Cannabis Dependence clinical trials
Every US clinical trial registered for Cannabis Dependence — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
13 US clinical trials · 2 currently recruiting
The research picture
Cannabis Dependence has 13 registered US clinical trials, 2 of them open to new participants right now — about 15% of the total.
- 2
- recruiting participants now
- 15%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 2
- top sponsor: National Institute on Drug Abuse (NIDA)
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Yale University
NCT01730781
Neuroimaging of Adolescent Cannabis Use Treatment
Indiana University
NCT07340554
Breathwork-assisted Treatment for Cannabis Use Disorder
Elias Dakwar
NCT05219825
Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms
National Institute on Drug Abuse (NIDA)
NCT01603992
Improving Substance Use and Clinical Outcomes in Heavy Cannabis Users With Quetiapine
Northwell Health
NCT01153490
Risk Perception in Drug-Dependent Adults With and Without Schizophrenia
National Institute on Drug Abuse (NIDA)
NCT01031563
Treatment for Cannabis Withdrawal and Dependence
The Scripps Research Institute
NCT01611948
Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal
Yale University
NCT01618656
Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders
Louisiana State University and A&M College
NCT01875796
Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
Hunter Holmes Mcguire Veteran Affairs Medical Center
NCT03662529
Targeting Tobacco Cessation During Treatment for Cannabis Use Disorders
Dartmouth-Hitchcock Medical Center
NCT01834794
An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents
Medical University of South Carolina
NCT00542750
Reducing Cannabis Overuse With Prazosin
VA Puget Sound Health Care System
NCT04721353
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cannabis Dependence Trial Landscape
ClinicalTrials.gov lists 13 US studies indexed under Cannabis Dependence, and 2 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cannabis Dependence shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cannabis Dependence is led by National Institute on Drug Abuse (NIDA) with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cannabis Dependence?
PlainTrial tracks 13 US clinical trials for Cannabis Dependence, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cannabis Dependence?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.