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ClinicalTrials.gov 2 recruiting now official registry

Advanced Malignancies clinical trials

2 of 11 indexed Advanced Malignancies trials are currently recruiting.

11 US clinical trials · 2 currently recruiting

Advanced Malignancies is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis Pharmaceuticals, running 2 of these trials.

The research picture

Advanced Malignancies has 11 registered US clinical trials, 2 of them open to new participants right now, about 18% of the total.

2
recruiting participants now
18%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Novartis Pharmaceuticals
Phase 19Phase 32

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 1 176 participants

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

BioInvent International AB

NCT04752826

RECRUITING Phase 3 50 participants

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Novartis Pharmaceuticals

NCT06401356

ACTIVE NOT RECRUITING Phase 3 68 participants

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Pfizer

NCT05059522

ACTIVE NOT RECRUITING Phase 1 40 participants

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Arcus Biosciences

NCT05891171

COMPLETED Phase 1 398 participants

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

Regeneron Pharmaceuticals

NCT02383212

COMPLETED Phase 1 58 participants

A Phase 1 Multicenter Open-label Study to Evaluate the Safety Tolerability and PK of MEDI0680 (AMP-514) in Subjects With Advanced Malignancies

MedImmune

NCT02013804

COMPLETED Phase 1 46 participants

Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)

Astellas Pharma

NCT01284192

COMPLETED Phase 1 24 participants

Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen

Astellas Pharma Global Development

NCT04837196

COMPLETED Phase 1 14 participants

Safety Study of Two Oral Formulations of MGCD265 Administered in Healthy Subjects in the Fasting State

Mirati Therapeutics

NCT01930006

COMPLETED Phase 1 14 participants

A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function

Novartis Pharmaceuticals

NCT00421044

COMPLETED Phase 1 2 participants

Maintenance Study on the Long Term Safety of XL999

Symphony Evolution

NCT00955084

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Advanced Malignancies Trial Landscape

11 indexed Advanced Malignancies studies · 2 recruiting (18%).

Phase mix: 2 late (III/IV) vs 9 early (I/II).

Top sponsor: Novartis Pharmaceuticals (2 trials), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Advanced Malignancies?

PlainTrial tracks 11 US clinical trials for Advanced Malignancies, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Advanced Malignancies?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.