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ClinicalTrials.gov enrollment closed early-phase tilt small index

Adult Gliosarcoma: early-phase trial registry

A small indexed set (13 trials) with no open enrollment listed right now.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · none currently recruiting · #1,315 of 28,707 conditions by registered trial count

Adult Gliosarcoma: 13 US clinical trials tracked, none currently recruiting.

Adult Gliosarcoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition adult-gliosarcoma

OPEN 0 | RECR 0% | LATE 0 | EARLY 13 | RANK #1315 | SPON 6

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Adult Gliosarcoma (this)0%
Open-enrollment share among volume-matched conditions near Adult Gliosarcoma

Adult Gliosarcoma has no open enrollment in this registry pull (13 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Adult Gliosarcoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Adult Gliosarcoma is recruiting below its size-band peers.

    0 of 13 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Adult Gliosarcoma research.

    National Cancer Institute (NCI) accounts for 6 of 13 trials (46.2%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Most Adult Gliosarcoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 25 among the 13 trials that report a genuine target (sentinel values excluded). 12 of those (92.3%) plan for fewer than 100 participants.

  4. Adult Gliosarcoma research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 23

Indexed trials (enrollment closed)

13 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 1 83 participants

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

National Cancer Institute (NCI)

NCT00268385

COMPLETED Phase 1 136 participants

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

National Cancer Institute (NCI)

NCT00045110

COMPLETED Phase 1 69 participants

Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma

National Cancer Institute (NCI)

NCT00112736

COMPLETED Phase 2 56 participants

Erlotinib and Sorafenib in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

National Cancer Institute (NCI)

NCT00445588

COMPLETED Phase 2 44 participants

GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

National Cancer Institute (NCI)

NCT00980343

COMPLETED Phase 2 33 participants

Dovitinib in Treating Patients With Recurrent or Progressive Glioblastoma

Manmeet Ahluwalia, MD

NCT01753713

COMPLETED Phase 1 25 participants

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Sanjiv Sam Gambhir

NCT01806675

COMPLETED Phase 1 17 participants

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT02186509

COMPLETED Phase 1 16 participants

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

City of Hope Medical Center

NCT02015819

COMPLETED Phase 1 15 participants

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

City of Hope Medical Center

NCT01172964

COMPLETED Phase 1 12 participants

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

National Cancer Institute (NCI)

NCT00004262

COMPLETED Phase 1 12 participants

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Virginia Commonwealth University

NCT02337426

COMPLETED Phase 1 7 participants

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

City of Hope Medical Center

NCT01234740

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 3

Named interventions

Most-linked intervention names on Adult Gliosarcoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

pharmacological study Other
7 trials
laboratory biomarker analysis Other
5 trials
flucytosine Drug
2 trials
erlotinib hydrochloride Drug
2 trials
therapeutic conventional surgery Procedure
2 trials
Temozolomide Drug
2 trials
gene therapy Biological
1 trials
polymerase chain reaction Other
1 trials

US sites by state

Facility locations filed on Adult Gliosarcoma trials. A trial with sites in several states counts in each.

California 8 trials
Pennsylvania 6 trials
Ohio 5 trials
Maryland 4 trials
Massachusetts 4 trials
Wisconsin 3 trials
Texas 3 trials
North Carolina 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Adult Gliosarcoma page

13 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Adult Gliosarcoma trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • National Cancer Institute (NCI) sponsors the most Adult Gliosarcoma trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Adult Gliosarcoma condition card totals 13 registered trials; most-linked intervention pharmacological study; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.