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NCT00045110 · ClinicalTrials.gov registry record · Phase 1

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

A Phase 1 study of Adult Glioblastoma and Adult Giant Cell Glioblastoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
136
Enrollment target
7
Study locations

NCT00045110 is a Phase 1 study of Adult Glioblastoma and Adult Giant Cell Glioblastoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 136 participants, above the 34-participant average among 14 other Adult Glioblastoma trials with a reported enrollment target (300% higher). The trial reports 7 study locations across 6 states.

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The verdict

NCT00045110, a Phase 1 study of Adult Glioblastoma and Adult Giant Cell Glioblastoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
136 participants
Enrollment target
7
Study locations

Study Summary

Phase I/II trial to study the effectiveness of erlotinib in treating patients who have recurrent malignant glioma or recurrent or progressive meningioma. Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • DRUG erlotinib hydrochloride

Study Locations (7)

California

  • University of California Los Angeles - Los Angeles
  • University of California San Francisco - San Francisco

Maryland

  • National Cancer Institute Neuro-Oncology Branch - Bethesda

New York

  • Memorial Sloan Kettering Cancer Center - New York

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Texas

  • University of Texas Southwestern Medical Center - Dallas

Wisconsin

  • University of Wisconsin - Madison

Trial Details

FieldValue
Enrollment Target 136 participants
Start Date 2002-08
Est. Completion 2010-12
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00045110

The ClinicalTrials.gov registry entry for NCT00045110 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 34-participant average among 14 other Adult Glioblastoma trials with a reported enrollment target (300% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Adult Glioblastoma appearing as the primary indexed condition, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT00045110 reports 7 study locations spanning 6 distinct geographic areas - top geographies include California, Maryland, New York.

Frequently Asked Questions

What is clinical trial NCT00045110 about?

NCT00045110 is a clinical study titled "Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma". Phase I/II trial to study the effectiveness of erlotinib in treating patients who have recurrent malignant glioma or recurrent or progressive meningioma. Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.

What is the current status of trial NCT00045110?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 136 participants. The study started on 2002-08. Estimated completion is 2010-12.

What conditions does trial NCT00045110 study?

This clinical trial studies the following conditions: Adult Glioblastoma, Adult Giant Cell Glioblastoma, Adult Gliosarcoma, Recurrent Adult Brain Tumor, Adult Anaplastic Astrocytoma.

What interventions are being tested in trial NCT00045110?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), erlotinib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00045110?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00045110 being conducted?

This trial has 7 study locations across California, Maryland, New York, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.