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NCT05597306 · ClinicalTrials.gov registry record · Phase 1

Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia

A Phase 1 study of Acute Myeloid Leukemia and Refractory Acute Myeloid Leukemia, sponsored by Terrence J Bradley, MD.

Recruiting
Registry status
Phase 1
Development phase
18
Enrollment target
1
Study location

NCT05597306 is a Phase 1 study of Acute Myeloid Leukemia and Refractory Acute Myeloid Leukemia that is actively recruiting participants, run by Terrence J Bradley, MD. The registered enrollment target is 18 participants, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05597306, a Phase 1 study of Acute Myeloid Leukemia and Refractory Acute Myeloid Leukemia, is actively recruiting participants, sponsored by Terrence J Bradley, MD.

RECRUITING
Registry status
Phase 1
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

This study aims to learn about the safety, tolerability, and different dose levels' safety profiles of Venetoclax and Bomedemstat (VenBom) combination therapy in participants with relapsed or refractory acute myeloid leukemia.

Conditions Studied

Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia Acute Myeloid Leukemia, in Relapse

Interventions

  • DRUG Venetoclax
  • DRUG Bomedemstat

Study Locations (1)

Florida

  • University of Miami - Miami

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2022-11-19
Est. Completion 2026-11-19
Phase Phase 1

Sponsor

Terrence J Bradley, MD

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05597306

The ClinicalTrials.gov registry entry for NCT05597306 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (84% lower). The listed sponsor is Terrence J Bradley, MD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Venetoclax is the first listed.

NCT05597306 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05597306 about?

NCT05597306 is a clinical study titled "Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia". This study aims to learn about the safety, tolerability, and different dose levels' safety profiles of Venetoclax and Bomedemstat (VenBom) combination therapy in participants with relapsed or refractory acute myeloid leukemia.

What is the current status of trial NCT05597306?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2022-11-19. Estimated completion is 2026-11-19.

What conditions does trial NCT05597306 study?

This clinical trial studies the following conditions: Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse.

What interventions are being tested in trial NCT05597306?

The interventions under investigation include: Venetoclax (DRUG), Bomedemstat (DRUG).

Who is sponsoring clinical trial NCT05597306?

This trial is sponsored by Terrence J Bradley, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05597306 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.