Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00685659 · ClinicalTrials.gov registry record · NA
Effectiveness of Extended Treatments for Drug Dependence
A NA study of Cocaine Dependence, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 332
- Enrollment target
- 2
- Study locations
NCT00685659: Completed NA study of Cocaine Dependence, sponsored by University of Pennsylvania.
NCT00685659 is a NA study of Cocaine Dependence that has completed, run by University of Pennsylvania. The registered enrollment target is 332 participants, above the 290-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (14% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00685659, a NA study of Cocaine Dependence, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 332 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study tests the effectiveness of two 24 month, telephone-based adaptive continuing care interventions for patients with cocaine dependence. The two interventions are predicted to produce better drug use outcomes than standard care. Furthermore, the intervention that also includes monetary incentives for continued participation is hypothesized to produce better retention and drug use outcomes than the intervention without incentives. Economic analyses will determine the cost-effectiveness and benefit-cost of the interventions relative to standard care, and to each other.
Primary Outcome
Abstinence as reported on Addiction Severity Index, Timeline Follow up, and as tested on the urine drug screen. Measure was created as such: if on ASI the participant reported no use, and on the TLFB the participant reported no use, and on the urine drug screen there was no substances detected, then the participant is considered abstinent. If there is use indicated on any one or all of those items (ASI, TLFB, UDS) then the participant is not abstinent.
Conditions Studied
Interventions
- OTHER Intensive Outpatient Treatment
- OTHER Adaptive telephone-based counseling
- OTHER Adaptive telephone-based counseling plus incentives
Study Locations (2)
Pennsylvania
- Presbyterian Hospital - Philadelphia
- NorthEast Treatment Centers - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 332 participants |
| Start Date | 2007-05 |
| Est. Completion | 2011-12 |
| Phase | NA |
What the finished NCT00685659 record still lists
NCT00685659 is an interventional study that assigns participants to a tested intervention. The registered 332 participants enrollment target is mid-sized for trials with a published cap, above the 290-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (14% higher).
The record links to 1 condition, with Cocaine Dependence appearing as the primary indexed condition, and to 3 interventions - of which Intensive Outpatient Treatment is the first listed.
NCT00685659 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00685659 about?
NCT00685659 is a clinical study titled "Effectiveness of Extended Treatments for Drug Dependence". This study tests the effectiveness of two 24 month, telephone-based adaptive continuing care interventions for patients with cocaine dependence. The two interventions are predicted to produce better drug use outcomes than standard care. Furthermore, the intervention that also includes monetary incen...
What is the current status of trial NCT00685659?
This trial is currently completed. It is a NA study. The enrollment target is 332 participants. The study started on 2007-05. Estimated completion is 2011-12.
What conditions does trial NCT00685659 study?
This clinical trial studies the following conditions: Cocaine Dependence.
What interventions are being tested in trial NCT00685659?
The interventions under investigation include: Intensive Outpatient Treatment (OTHER), Adaptive telephone-based counseling (OTHER), Adaptive telephone-based counseling plus incentives (OTHER).
Who is sponsoring clinical trial NCT00685659?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00685659 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine Dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00685659's enrollment target sits among peer trials
332 2nd of 38 the highest of 38 other Cocaine Dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine Dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder
RECRUITING · NA
-
Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2
COMPLETED · NA
-
Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
COMPLETED · NA
-
Exercise as a Behavioral Treatment for Cocaine Dependence
COMPLETED · NA
-
Modafinil, Sleep, and Cognition in Cocaine Dependence
COMPLETED · NA
-
Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01174121 · 332 participants · Phase 2
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
- NCT02605785 · 332 participants · NA
A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy
- NCT04894006 · 332 participants · NA
Dementia Family Caregiver Study
- NCT05130606 · 332 participants · NA
CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia